Clinical trial Recruiting at 1 site Observational Ages 18 and up

How movement and nervous system function relate after stroke

Official title: SOMADC-CC (SOMAtic Dysfunction Characterization Following Chronic Cerebrovascular Disease): Biomarker Study

Run by University of California, Davis · NCT07737873 · Data updated 2026-11-12

This study tests whether measures of movement efficiency and nerve function relate to outcomes in adults who had a stroke.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment100 (estimated)
SponsorUniversity of California, Davis
Academic / other
Locations1 site (Sacramento, California)
StatusRecruiting
StartedJuly 1, 2026
Main results expectedJune 30, 2028
Study endsJune 30, 2028
Registry record updatedJuly 30, 2026
Trial IDNCT07737873 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18 and older with a history of ischemic stroke, able to sit, lie in various positions, and walk independently with or without aids, who can consent or have an LAR.

Probably not a fit

Individuals unlikely to benefit may include those unable to participate in the required assessments or who do not experience measurable changes in the studied parameters.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines connections between musculoskeletal function, movement efficiency, and nervous system function in people who had a stroke. Researchers use a novel osteopathic examination approach called the Functional Pathology of the Musculoskeletal System (FPMSS) to quantify somatic dysfunction. The study builds on prior work suggesting early changes after ischemic stroke, and aims to see how these factors correlate with patient-reported outcomes and quality of life. Participants are adults with a prior stroke, recruited from UC Davis Stroke Clinic, who can sit, stand, and walk with or without aids. Data collection includes clinical exams and surveys delivered via SMS or email.

Why it matters

Potential benefit: If the approach proves informative, it could improve understanding of post-stroke disability and guide personalized care strategies.

How similar studies have gone: Previous work suggests that somatic dysfunction can be quantified and may relate to neurological status, but this specific approach in chronic stroke is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* • UC Davis Stroke Clinic outpatient patients \>3 months from previous stroke

  * Adults ≥18 years
  * Previous admission diagnosis or referral indication:

    o Ischemic stroke (prior history of)
  * Able to sit upright, lie supine, and lie lateral recumbent left/right positions
  * Must be able to walk independently with/without walking aids.
  * Participants must have the capacity to consent to study participation themselves or have a Legally Authorized Representative (LAR) available.
  * Willingness to receive SMS (text) messages and/or email to complete REDCap QoL survey

Exclusion Criteria:

* • Acute skeletal fracture or known dislocation; history of pathologic (osteoporotic or neoplastic) skeletal fracture of thoracic cage, hip/pelvis/sacrum, or vertebral column

  * Spinal column support brace (e.g. cervical collar)
  * History of spinal cord injury with residual neuromuscular or sensory disability
  * Clinical condition that would interfere with execution of movement or palpatory diagnostic testing, e.g. prohibitive chronic pain
  * Participants who have received either OMT or chiropractic manipulation following their stroke and prior to enrollment.

Where it's running

  • University of California Davis
    Sacramento, California, United States
    Recruiting

Study contacts

  • Principal investigator: Alan Yee, D.O. — University of California, Davis
  • Study coordinator: Alan Yee, D.O.
  • Email: ahyee@ucdavis.edu
  • Phone: 916-734-3588

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.