Measuring functional proteins in women with polycystic ovary syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to measure and compare the concentrations of functional proteins such as kisspeptin, ghrelin, and zonulin in women with polycystic ovary syndrome (PCOS) who have insulin resistance, those with PCOS without insulin resistance, and women without PCOS. The study seeks to identify potential markers of insulin resistance that could be used for early diagnosis and intervention. By utilizing simpler diagnostic methods like HOMA-IR and fasting insulin measurements, the research aims to enhance understanding of the metabolic disturbances associated with PCOS and their long-term health implications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* women aged 18-45 years

Exclusion Criteria:

* removal of at least one ovary
* treated diabetes of any type
* diagnosed and treated metabolic diseases
* diagnosed and treated autoimmune diseases
* diagnosed and treated autoinflammatory diseases

Where it's running

• Jagiellonian University
  Krakow, Poland Recruiting

Study contacts

• Study coordinator: Iwona Gawron, Ph.D., M.D.
• Email: iwona.gawron@uj.edu.pl
• Phone: +48 124248570

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Investigating inflammatory markers in women with PCOS

  This study is testing the levels of certain inflammatory markers in women with polycystic ovary syndrome (PCOS) to see how they compare to women without PCOS and to understand their connection to insulin resistance.

  Recruiting Jagiellonian University · Krakow · NCT06793085

• Ovarian drilling via vNOTES laparoscopy for PCOS patients

  This study tests whether drilling the ovaries using vNOTES laparoscopy can help women with PCOS who did not respond to first-line medicines.

  Recruiting University Hospital, Clermont-Ferrand · Clermont-Ferrand · NCT07923552

• PMOS and Sleep Apnea: A Pilot Look at Mitochondrial Function

  In women with PMOS, this pilot study tests whether sleep apnea treatment with CPAP improves mitochondrial function in leg muscle tissue.

  Recruiting University of Chicago · Chicago, Illinois · NCT07871149

• Lean Beef as Part of a Healthy Meal Plan for Adolescent Girls with PCOS/PMOS

  This pilot study tests a lean beef–based meal plan to see if it improves blood sugar control and diet quality in adolescent girls with PCOS/PMOS.

  Recruiting Texas A&M University · College Station, Texas · NCT07780188

• Inositol and Metformin with Mediterranean or Low-Carb Diets in Women with PCOS

  This trial tests whether adding inositol, metformin, or folic acid to either a Mediterranean or a low-carbohydrate diet helps women with PCOS and insulin resistance lose weight and improve metabolic markers.

  Recruiting Dicle University · Diyarbakır, Diyarbakır · NCT07770711

• Fecal microbiota transplantation for overweight women with PMOS undergoing embryo transfer

  We are testing if oral FMT capsules are safe and can improve pregnancy outcomes for overweight/obese women with PMOS undergoing frozen embryo transfer.

  Recruiting Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT07746635

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.