Clinical trial Recruiting at 1 site Observational Ages 18 and up

Measuring Exhaled Gas Temperature to See if Passive Humidification Keeps Air Humid for Intubated Patients

Official title: Measurement of Expiratory Gas Temperature in Intubated Patients to Estimate Expiratory Absolute Humidity

Run by Laval University · NCT07420673 · Data updated 2026-11-12

This study tests whether measuring the temperature of exhaled air in intubated ICU patients who use passive humidification can help estimate the humidity delivered to the lungs.

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Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment70 (estimated)
SponsorLaval University
Academic / other
Locations1 site (Québec, Quebec)
StatusRecruiting
StartedMay 25, 2026
Main results expectedDecember 2027
Study endsJune 2028
Registry record updatedNovember 5, 2026
Trial IDNCT07420673 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18 and older who are intubated and on mechanical ventilation with passive humidification in the ICU.

Probably not a fit

Patients not using passive humidification or with incompatible ventilation settings may not benefit from this measurement approach.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In intubated ICU patients, keeping the air moist is important to prevent thick secretions. This observational study will measure the temperature of exhaled gases to estimate absolute humidity during expiration. The goal is to better reproduce real clinical conditions in bench testing and to improve how heat and moisture exchangers are evaluated. Data from these measurements may help standardize humidification assessments across different patient temperatures and body states.

Why it matters

Potential benefit: If successful, the results could improve bench tests and device evaluations for humidification devices, leading to more accurate matching of humidification to patient needs.

How similar studies have gone: Previous work suggests a relationship between expiratory temperature and humidity, but data for awake/ICU patients are limited and more validation is needed.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults (≥18 years)
* Intubated and mechanically ventilated in the intensive care unite
* Using passive humidification (Heat and Moisture exchanger)

Exclusion Criteria:

* PEEP set \< 12 cmH₂O
* Inhaled nitric oxide therapy
* Tracheostomy

Where it's running

  • Insitut universitaire de cardiologie et de pneumologie de Quebec - Universite Laval
    Québec, Quebec, Canada
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.