Male Hypogonadism: How Stigma and Identity relate to Quality of Life

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study compares levels of anticipated illness stigma and illness identity in men with hypogonadism to age‑matched men with other chronic endocrine diseases seen in the same clinic. It also explores whether these psychosocial factors predict quality‑of‑life changes within the hypogonadism group. Participants are adult men, with cases having biochemically confirmed hypogonadism and controls having diabetes, hypertension, or hypothyroidism, all under endocrinology care. Inclusion requires Turkish literacy and informed consent; exclusion criteria include active psychiatric illness and certain inflammatory or rheumatic diseases. The study is led by Hacettepe University with collaboration from Turkish clinical sites in Bingöl and Malatya.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Cases:

* Male, aged 18 years or older.
* Biochemically confirmed hypogonadism (total testosterone \< 300 ng/dL with at least one clinical symptom).
* Regular follow-up at the endocrinology outpatient clinic.
* Fluent in reading and understanding Turkish.
* Signed informed consent.

Controls:

* Male, aged 18 years or older.
* Diagnosed with diabetes, hypertension, or hypothyroidism under regular endocrinology follow-up.
* Total testosterone ≥ 300 ng/dL.
* Age-matched to a participant in the case group (±5 years).
* Fluent in reading and understanding Turkish.
* Signed informed consent.

Exclusion Criteria:

* Active psychiatric diagnosis (e.g., active psychosis, bipolar disorder).
* Chronic inflammatory or rheumatological diseases affecting body composition (e.g., chronic kidney disease, IBD, rheumatoid arthritis, SLE, ankylosing spondylitis).
* Uncontrolled co-existing endocrine conditions or severe complications (e.g., HbA1c \> 8.0%, diabetic neuropathy/nephropathy/retinopathy, non-euthyroid state).
* Cognitive impairment or dementia precluding questionnaire completion.
* Klinefelter syndrome.
* Literacy limitations preventing completion of self-report measures.
* Additional control exclusion: Diagnosis or clinical suspicion of hypogonadism.

Where it's running

• Bingöl University Faculty of Physical Therapy and Rehabilitation
  Bingoel, Turkey (Türkiye) Recruiting
• Malatya Training and Research Hospital
  Malatya, Turkey (Türkiye) Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Environmental and inflammatory links to metabolic and endocrine diseases

  This project will see if combining environmental, genetic, and protein information can help predict early risk of diabetes, hypertension, and other metabolic or endocrine problems in community adults.

  Recruiting Chongqing Medical University · Chongqing · NCT07512609

• Using low-dose aspirin after preeclampsia to improve recovery

  This study is testing if taking low-dose aspirin for six months after having preeclampsia can help new moms recover better by improving their blood pressure and blood vessel function.

  Recruiting Phase 4 University of Pittsburgh · Pittsburgh, Pennsylvania · NCT06281665

• Exercise Self-Efficacy, Body Composition, and Activity in Men with Low Testosterone

  This study tests how confident men on testosterone therapy are at staying active and whether that confidence links body fat and lean mass with how much they exercise.

  Recruiting at 2 sites Hacettepe University · Bingoel and 1 other locations · NCT07924514

• IMB-guided health education to boost medication taking and blood pressure control in adults with hypertension

  This study tests a health-literacy program based on Information-Motivation-Behavioral Skills to help adults with hypertension who don’t take their medicines regularly to take them more consistently and better control their blood pressure.

  Recruiting at 8 sites Bahir Dar University · Ādēt and 7 other locations · NCT07894068

• Renal Nerve Stimulation to Help Blood Pressure in AF and HFpEF

  This study tests whether stimulating the kidneys with a catheter can safely lower blood pressure in adults with atrial fibrillation and HFpEF who also have hypertension.

  Recruiting London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · London, Ontario · NCT07893821

• Hypertension: Does Education Help Patients Manage Blood Pressure Better?

  This study tests whether structured patient education improves blood pressure control and self-management in adults with hypertension who speak Turkish.

  Recruiting Inonu University · Batman, Center · NCT07890090

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.