Environmental and inflammatory links to metabolic and endocrine diseases
Official title: Environment, Inflammation and Metabolic Diseases Study
Run by Chongqing Medical University · NCT07512609 · Data updated 2026-11-12
This project will see if combining environmental, genetic, and protein information can help predict early risk of diabetes, hypertension, and other metabolic or endocrine problems in community adults.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 8000 (estimated) |
| Sponsor | Chongqing Medical University Academic / other |
| Locations | 1 site (Chongqing) |
| Status | Recruiting |
| Started | December 25, 2020 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | April 6, 2026 |
| Trial ID | NCT07512609 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults from the local community who voluntarily attend physical examinations, can provide blood and urine samples, and agree to regular follow-up are ideal candidates.
✕Probably not a fit
People who cannot commit to follow-up visits, refuse sample collection, or have incomplete data are unlikely to benefit from the project.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational cohort will create a resource database from about 8,000 community participants in Chongqing who have been followed for over five years. Participants receive clinical, biochemical, and endpoint event assessments every two years and provide blood and urine samples for molecular analysis. Researchers will apply whole-transcriptome sequencing, proteomics and phosphoproteomics, ATAC-seq, and single-cell sequencing to build an environment-gene-protein panoramic network. The goal is to identify population-level risk factors, clarify molecular mechanisms of disease onset and progression, and screen for potential therapeutic targets.
Why it matters
Potential benefit: If successful, the project could provide earlier, more personalized warnings of metabolic disease risk and reveal new targets for prevention or treatment.
How similar studies have gone: Previous large cohorts and multi-omics studies have identified biomarkers and pathways in metabolic disease, but integrating environmental, gene, and protein data into a panoramic population-level network is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All individuals who voluntarily participated in the physical examination Exclusion Criteria: Participants with incomplete data
Where it's running
-
The First Affiliated Hospital of Chongqing Medical University
Chongqing, China Recruiting
Study contacts
- Principal investigator: Qifu Li, MD, PhD, Chief Physician — First Affiliated Hospital of Chongqing Medical University
- Study coordinator: Qifu Li, MD, PhD, Chief Physician
- Email: liqifu@yeah.net
- Phone: +8618696676815
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.