Clinical trial Recruiting at 1 site Interventional Ages 6 to 8

Lower-extremity constraint therapy to improve walking in children with hemiplegic CP

Official title: Effect of Lower Extremity Modified Constraint-induced Movement Therapy on Locomotion in Children With Hemiplegia

Run by Cairo University · NCT07686809 · Data updated 2026-11-12

This study tests modified constraint-induced movement therapy for improving how children with spastic hemiplegic cerebral palsy walk.

Quick facts

Study typeInterventional
Ages6 Years to 8 Years
SexAll
Enrollment30 (estimated)
SponsorCairo University
Academic / other
Locations1 site (Cairo)
StatusRecruiting
StartedJune 1, 2026
Main results expectedJuly 30, 2026
Study endsAugust 30, 2026
Registry record updatedJuly 7, 2026
Trial IDNCT07686809 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Children aged 6–8 with spastic hemiplegic CP, Gross Motor Function Classification System levels I–II, pediatric balance scale 41–56, and ability to follow instructions.

Probably not a fit

Children with more severe impairment, fixed lower-extremity deformities, recent botulinum toxin, or major cardiac/lung issues may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares modified constraint-induced movement therapy with conventional physical therapy to see how each affects gait speed, step length, and balance in children with spastic hemiplegic cerebral palsy. Participants are 6 to 8 years old with mild-moderate spasticity and functional limitations who can follow commands. The trial examines changes in spatial and temporal gait parameters and overall functional mobility resulting from the two rehabilitation approaches. Outcomes will help clarify whether restricting the unaffected limb can boost locomotor performance in this population.

Why it matters

Potential benefit: If successful, the therapy could enhance walking speed, symmetry, and balance for children with hemiplegic CP.

How similar studies have gone: Previous approaches using constraint-based therapy have shown potential benefits in motor function, but evidence for lower-extremity gait outcomes remains mixed.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. The age of the selected children will range from 6 to 8 years old.
2. Degree of spasticity will range from 1+ to 2 according to the modified Ashworth scale.
3. The level of motor function of the children will be levels I-II according to the Gross Motor Function Classification System.
4. Participants will present a score between 41 to 56 points on the pediatric balance scale.
5. They will be able to follow instructions and understand commands.

Exclusion Criteria:

1. Bone and tendon lengthening surgeries within the last 6 months.
2. Lung and heart diseases and disorders.
3. Vision or hearing problems.
4. Children with fixed deformities in the lower extremity.
5. Children with epilepsy.
6. Recent intramuscular Botulinum toxin injection.

Where it's running

  • outpatient clinic faculty of physical therapy, Cairo University
    Cairo, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.