Video Microscope vs Loupe-Assist in Varicocelectomy
Official title: Comparative Study Between Video Telescopic Operating Microscope (VITOM) and Loupe- Assisted Varicocelectomy (Randomized Controlled Trial)
Run by Cairo University · NCT07916285 · Data updated 2026-11-12
This study tests whether using a video telescopic operating microscope (VITOM) provides better outcomes and surgeon satisfaction than loupe-assisted varicocelectomy in adult men with grade II/III varicoceles.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 60 Years |
| Sex | Men only |
| Enrollment | 60 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | November 1, 2025 |
| Main results expected | November 30, 2026 |
| Study ends | November 30, 2026 |
| Registry record updated | November 4, 2026 |
| Trial ID | NCT07916285 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are men 18-60 with grade II/III unilateral or bilateral varicocele who have persistent swelling or pain or infertility with impaired semen parameters and have not responded to medical treatment.
✕Probably not a fit
Patients with subclinical or grade 1 varicocele, acute infection, hormonal disorders, small testicular volume, or other exclusion criteria may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults aged 18 to 60 with grade II or III varicocele are randomized to undergo subinguinal varicocelectomy using either a video telescopic operating microscope (VITOM) or loupe magnification. Surgeons perform the procedure with magnification in both arms, aiming to compare efficacy, outcomes, and satisfaction. Varicocele patients often experience improved semen parameters and fewer complications when magnification is used, and this trial specifically evaluates whether VITOM offers advantages over loupe assistance. The study is conducted at Cairo University with a focus on surgical technique, perioperative factors, and early postoperative results.
Why it matters
Potential benefit: If successful, VITOM could improve surgical precision and patient outcomes in varicocelectomy.
How similar studies have gone: Prior use of magnification (microscope or loupe) has been associated with improved visualization and outcomes in varicocelectomy, suggesting potential benefit for VITOM; novelty lies in direct comparison with loupe assistance.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age: male patients from 18 - 60 years. * Males with grade II or III varicocele (unilateral or bilateral). * Males complaining of scrotal swelling or pain not responding to medical treatment. * Infertile males with impaired semen parameters. Exclusion Criteria: * Patients with subclinical varicocele or grade 1 varicocele. * Acute urogenital infection. * Patients with hypogonadism (hypogonadotrophic or hypergonadotrophic) * Patients with hyperprolactenemia. * Patient with small testicular volume.
Where it's running
-
Cairo University
Cairo, Egypt Recruiting
Study contacts
- Study coordinator: Mohamed A Mahmoud, MSc
- Email: galal241019888@gmail.com
- Phone: 00201559589004
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.