Longitudinal database for patients with gastroparesis symptoms

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The GOLDEN project is a longitudinal database that tracks patients with symptoms of gastroparesis at the University of Louisville, starting from 2012 and continuing to the present. It includes both current patients and legacy patients from other centers, allowing for comprehensive data collection on symptoms, survival, quality of life, and various health measures over time. The study evaluates outcomes regardless of treatment and stratifies results based on different interventions, including GI neuromodulation and immunotherapy. This extensive data collection aims to provide insights into the management and effects of gastroparesis.

Why it matters

Who can join: the full rules

Inclusion:

* Patients with the symptoms (Sx) of drug refractory gastroparesis
* Disordered nutrition by standardized assessment
* Ability to assess current symptom status
* Ability to measure other medical conditions

Exclusion:

* Anatomic obstruction of the GI Tract
* Pregnancy
* Inability of patient or guardian to sign informed consent, if needed
* Psychiatric disorders precluding assessment and treatment of the patient's GI condition

Where it's running

• University of Louisville
  Louisville, Kentucky, United States Recruiting

Study contacts

• Principal investigator: Thomas Abell, MD — University of Louisville
• Study coordinator: Thomas Abell, MD
• Email: thomas.abell@louisville.edu
• Phone: (502)852-6991

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Gastric-focused ultrasound to see if it changes stomach activity and symptoms

  This study tests whether noninvasive stomach-focused ultrasound can alter post-meal stomach electrical activity and symptoms in adults with gastroparesis or delayed gastric emptying, using a sham control in a crossover design.

  Recruiting University of Texas at Austin · Austin, Texas · NCT07851727

• Gastric emptying and feeding tolerance in ICU patients by vasopressor dose

  This study tests whether vasopressor dose affects how well stomach contents empty during tube feeding in critically ill patients.

  Recruiting Başakşehir Çam & Sakura City Hospital · Istanbul · NCT07802379

• Virtual poetry workshops to boost well-being for people with digestive symptoms

  This study tests whether participating in online poetry workshops can improve emotional well-being for adults with chronic digestive symptoms and anxiety or depression.

  Recruiting Ohio State University · Columbus, Ohio · NCT07717541

• Risk prediction for gastric retention during sedated gastroscopy

  This study will test a simple grading system and prediction model to see if clinicians can identify which adults are likely to have significant stomach contents before sedated gastroscopy.

  Recruiting at 2 sites Zhejiang University · Hangzhou, Zhejiang and 2 other locations · NCT07104214

• Prokinetics and Body Surface Gastric Mapping in Dyspeptic Patients

  This study tests whether using Body Surface Gastric Mapping can help predict which medications will help people with gastroparesis or functional dyspepsia see improvement.

  Recruiting at 2 sites University of Auckland, New Zealand · Philadelphia, Pennsylvania and 2 other locations · NCT06854120

• Using Growth Hormone to Treat Gastroparesis

  This study is testing if Growth Hormone can help people with gastroparesis feel better when other treatments haven't worked.

  Recruiting at 2 sites Early Phase 1 Mayo Clinic · Phoenix, Arizona and 1 other locations · NCT06803589

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.