Long-term study of blood diseases in patients in China
Official title: National Longitudinal Cohort of Hematological Diseases (NICHE)
Run by Institute of Hematology & Blood Diseases Hospital, China · NCT04645199 · Data updated 2026-11-12
This study is trying to gather detailed information from patients in China with blood diseases like leukemia and multiple myeloma to better understand how these conditions affect their lives and treatment options.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 2300 (estimated) |
| Sponsor | Institute of Hematology & Blood Diseases Hospital, China Academic / other |
| Locations | 1 site (Tianjin, Tianjin Municipality) |
| Status | Recruiting |
| Started | December 1, 2020 |
| Main results expected | December 1, 2030 |
| Study ends | December 1, 2030 |
| Registry record updated | February 12, 2026 |
| Trial ID | NCT04645199 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients diagnosed with acute myeloid leukemia, multiple myeloma, or other specified hematological disorders.
✕Probably not a fit
Patients with serious concomitant diseases or those unable to comply with study requirements may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to create a large-scale prospective cohort of patients diagnosed with various hematological diseases, including acute myeloid leukemia and multiple myeloma, in China. It will collect comprehensive data on the incidence, risk factors, treatment methods, prognosis, and medical expenses associated with these conditions. By analyzing this data, the study seeks to fill the gap in existing research, which has been limited by smaller, single-center cohorts. The study will include patients diagnosed from January 1, 2020, and will gather information from medical records to ensure a thorough understanding of these diseases.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the management and treatment of hematological diseases, potentially improving patient outcomes.
How similar studies have gone: While there have been smaller cohort studies, this large-scale prospective approach is relatively novel in the field of hematology in China.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who were diagnosed with acute myeloid leukemia, multiple myeloma, hemophilia, aplastic anemia, leukemia, myelodysplastic syndrome, lymphoma, bleeding disorders or received bone marrow transplantation in the investigating hospitals from January 1, 2020. Exclusion Criteria: * Long-term follow-up information for patients is not available for any reason, such as not being available or having a serious concomitant disease. * Alcohol and drug addictions affect their ability to comply with study requirements. * According to the investigator, there are conditions that may endanger the patient's safety or affect his/her compliance.
Where it's running
-
Institute of Hematology & Blood Diseases Hospital
Tianjin, Tianjin Municipality, China Recruiting
Study contacts
- Study coordinator: Zhen Song, MD
- Email: cir@ihcams.ac.cn
- Phone: +86 02223909051
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.