Improving outcomes for stem cell transplant patients using an intervention website
Official title: Mosaic: RCT of a Digital Health Intervention for English- and Spanish-speaking Stem Cell Transplant Recipients
Run by Northwestern University · NCT06960993 · Data updated 2026-11-12
This study is testing if a special website can help adults with blood cancer feel better and improve their quality of life after a stem cell transplant compared to a regular educational website.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 356 (estimated) |
| Sponsor | Northwestern University Academic / other |
| Locations | 3 sites (Washington D.C., District of Columbia and 2 other locations) |
| Status | Recruiting |
| Started | April 28, 2025 |
| Main results expected | June 12, 2028 |
| Study ends | February 1, 2030 |
| Registry record updated | October 30, 2026 |
| Trial ID | NCT06960993 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 or older diagnosed with hematologic cancers who are scheduled for stem cell transplants and are proficient in English or Spanish.
✕Probably not a fit
Patients currently involved in other behavioral interventions targeting distress or those with severe cognitive impairments may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to determine if an intervention website called Mosaic can enhance patient-reported outcomes for adults with blood cancer undergoing stem cell transplants, compared to a standard educational website. Patients will be recruited before their scheduled transplant and randomly assigned to use either the intervention or control website throughout the study. They will complete assessments at baseline and at 2, 4, 6, and 8 months post-transplant to evaluate psychological distress, physical symptoms, and overall quality of life. The study seeks to understand if improvements in these areas are linked to factors like perceived preparedness and self-efficacy.
Why it matters
Potential benefit: If successful, this study could lead to improved psychological and physical well-being for patients undergoing stem cell transplants.
How similar studies have gone: Other studies have shown promise in using digital interventions to improve patient outcomes, suggesting that this approach may be effective.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosed with a hematologic cancer according to medical records * Scheduled for or preparing for scheduling of an allogeneic or autologous stem cell transplant at one of our study sites * Aged 18 or older (no upper limit) * English or Spanish Proficient * Interested in using a website to learn about stem cell transplant * Ability to understand and willingness to sign an informed consent document and comply with all study procedures Exclusion Criteria: * Currently participating in a behavioral intervention targeting distress, health-related quality of life, or symptoms * Undergoing the first in a planned tandem stem cell transplant * Unable to provide meaningful consent (severe cognitive impairment or language difficulties)
Where it's running
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Georgetown University School of Medicine
Washington D.C., District of Columbia, United States Recruiting -
Northwestern University Feinberg School of Medicine
Chicago, Illinois, United States Recruiting -
Hackensack Meridian Health
Nutley, New Jersey, United States Recruiting
Study contacts
- Study coordinator: Alexandra Psihogios, PhD
- Email: Alex.psihogios@northwestern.edu
- Phone: 312-503-3577
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.