Clinical trial Recruiting at 1 site Observational Ages 18 to 65

Long-term outcomes for patients recovering from hepatitis B related liver failure

Official title: The Investigation on Long-term Outcomes and Prognostic Factors of Patients With Hepatitis B Related Acute-on-chronic Liver Failure

Run by Third Affiliated Hospital, Sun Yat-Sen University · NCT04310787 · Data updated 2026-11-12

This study looks at the long-term health and recovery of people who have survived liver failure caused by hepatitis B to see how they are doing over time.

More Hepatitis B trials

Quick facts

Study typeObservational
Ages18 Years to 65 Years
SexAll
Enrollment300 (estimated)
SponsorThird Affiliated Hospital, Sun Yat-Sen University
Academic / other
Locations1 site (Guangzhou, Guangdong)
StatusRecruiting
StartedMay 15, 2020
Main results expectedDecember 31, 2024
Study endsDecember 31, 2024
Registry record updatedNovember 29, 2024
Trial IDNCT04310787 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 to 65 who have been diagnosed with hepatitis B associated chronic acute liver failure and survived more than 90 days post-hospitalization.

Probably not a fit

Patients with HIV infection, liver cancer, autoimmune liver diseases, or other serious conditions that significantly affect survival may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the long-term prognosis and risk factors for patients who have recovered from hepatitis B virus-related acute-on-chronic liver failure. It focuses on patients who survived more than 90 days post-hospitalization and analyzes their clinical data through retrospective methods. Additionally, the study includes follow-up surveys conducted via telephone to gather comprehensive long-term outcome data. The aim is to fill the gap in existing research regarding the long-term survival rates and prognostic factors for these patients.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the long-term health outcomes and management strategies for patients recovering from hepatitis B related liver failure.

How similar studies have gone: Previous studies have primarily focused on short-term survival rates, making this investigation into long-term outcomes a novel approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age from 18 to 65 years old;
* The diagnosis consistent with hepatitis b associated chronic acute liver failure;
* After hospitalization, the survival time \> 90 days;
* The inpatient clinical data are complete.

Exclusion Criteria:

* Human immunodeficiency virus infection or congenital immune deficiency diseases;
* Liver cancer and other tumors, autoimmune liver disease, genetic and metabolic liver disease, or other serious diseases that significantly affect patient survival;
* Other conditions that the researchers judged not appropriate for inclusion.

Where it's running

  • Third Affiliated Hospital of Sun Yat-sen University
    Guangzhou, Guangdong, China
    Recruiting

Study contacts

  • Principal investigator: Liang Peng, Doctor — Third Affiliated Hospital, Sun Yat-Sen University
  • Study coordinator: Lu Wang, Doctor
  • Email: wanglu910525@163.com
  • Phone: +8618814369232

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.