Long-term health study of vascular and liver risk factors in Lishui
Official title: Whole-life Investigation of Lishui Longevity Cohort Study
Run by The Fifth Affiliated Hospital of Wenzhou Medical University & Lishui Central Hospital · NCT07592962 · Data updated 2026-11-12
This study follows 4,500 adults in Lishui to see how screening and follow-up for stroke and related conditions might help prevent major diseases over time.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 30 Years to 80 Years |
| Sex | All |
| Enrollment | 4500 (estimated) |
| Sponsor | The Fifth Affiliated Hospital of Wenzhou Medical University & Lishui Central Hospital Academic / other |
| Locations | 1 site (Lishui, Zhejiang) |
| Status | Recruiting |
| Started | May 18, 2026 |
| Main results expected | May 31, 2036 |
| Study ends | May 31, 2036 |
| Registry record updated | May 18, 2026 |
| Trial ID | NCT07592962 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 30–80 who are permanent residents of Lishui City, willing to participate and provide informed consent.
✕Probably not a fit
Individuals with a prior diagnosis of malignant tumors or cardiovascular/cerebrovascular diseases, unstable health status, or inability to participate in follow-up may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an observational cohort study enrolling 4,500 residents aged 30–80 from Lishui City to establish a standardized screening and follow-up system for chronic multimorbidity. Participants will be divided into three groups using imaging and methylation-based tests to detect cerebrovascular changes, cancer risk, and liver health. The project aims to identify risk factors early, enable targeted interventions, and strengthen community prevention capacity for cardiovascular and cerebrovascular diseases. Data will inform whether structured screening can reduce the incidence of major chronic diseases in the population. No interventional treatments are specified within this description; the focus is on screening, monitoring, and follow-up over time.
Why it matters
Potential benefit: If successful, the approach could enable earlier detection and better prevention of stroke and other major chronic diseases in the community.
How similar studies have gone: Other longitudinal programs using imaging and methylation-based approaches have shown promise in risk stratification, but this specific combination in Lishui is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 30 to 80 years old; male-to-female ratio of 1:1; permanent residents in Lishui City; physically healthy; voluntary participation in the project with signed informed consent. Exclusion Criteria: * Individuals ever diagnosed with malignant tumors or cardiovascular and cerebrovascular diseases by physicians or other health professionals; those with unstable vital signs or an expected survival time of less than 3 months; participants with incomplete basic information, and those unable to cooperate with subsequent follow-up.
Where it's running
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Lishui Central Hospital
Lishui, Zhejiang, China Recruiting
Study contacts
- Study coordinator: Jingping Sun, PhD
- Email: lszxyysunjingping@yeah.net
- Phone: 86-18504713450
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.