Long-term follow-up for patients with corneal diseases
Official title: Dresden Corneal Disease and Treatment Study - Analysis for Quality Inspection of Follow-up and Treatment Procedures of Corneal Diseases of the Department of Ophthalmology (University Hospital Carl Gustav Carus Dresden)
Run by Technische Universität Dresden · NCT04251143 · Data updated 2026-11-12
This study looks at how well different treatments work for people with corneal diseases like keratoconus over the long term, to see how their eyes are doing after surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 700 (estimated) |
| Sponsor | Technische Universität Dresden Academic / other |
| Locations | 1 site (Dresden, Saxony) |
| Status | Recruiting |
| Started | March 12, 2018 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2030 |
| Registry record updated | February 28, 2023 |
| Trial ID | NCT04251143 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with corneal diseases, particularly those experiencing corneal ectasia or keratoconus.
✕Probably not a fit
Patients who are pregnant or under 18 years of age will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on the long-term follow-up of patients suffering from corneal diseases, particularly corneal ectasia and keratoconus. It aims to analyze the quality of surgical interventions, such as corneal cross-linking, and to monitor disease progression and corneal stability post-surgery. The study employs various diagnostic techniques, including biomicroscopy, optical coherence tomography, and corneal topography, to gather comprehensive data on patient outcomes. By closely examining these parameters, the study seeks to improve understanding of corneal disease management and treatment efficacy.
Why it matters
Potential benefit: If successful, this study could enhance treatment strategies for patients with corneal diseases, potentially improving visual outcomes and reducing the need for corneal transplants.
How similar studies have gone: Other studies have shown success with similar approaches in monitoring corneal diseases and evaluating surgical interventions.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * corneal disease * corneal ectasia Exclusion Criteria: * pregnancy * age under 18 years
Where it's running
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Department of Ophthalmology; Medical Faculty Carl Gustav Carus; Technical University Dresden
Dresden, Saxony, Germany Recruiting
Study contacts
- Study coordinator: Robert Herber, MSc
- Email: robert.herber@uniklinikum-dresden.de
- Phone: 004935145815091
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Corneal Crosslinking to Treat Progressive Keratoconus or Corneal Ectasia
This study tests two different light durations used in corneal crosslinking to see which better helps people with keratoconus or corneal ectasia.
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Evaluating a new system for treating corneal ectasia
This study is testing a new treatment system for people with corneal ectasia and keratoconus to see if it can help improve their eye health and vision.
-
Brillouin hydration mapping to study cornea health
Researchers test a Brillouin microscope to see if it can measure corneal water content in healthy people and those with eye conditions.
-
Smartphone-based AI eye disease screening for anterior segment conditions
A smartphone-powered AI system tests whether it can identify 16 eye conditions from images captured on a phone, without needing internet access, in adults.
-
Same-day bilateral corneal cross-linking for keratoconus
This trial tests whether performing corneal cross-linking in both eyes on the same day is safe and feasible for people with keratoconus.
-
Cord plasma eye drops to treat neuropathic corneal pain
This trial will test whether cord plasma eye drops can reduce long-lasting nerve-related corneal pain in people with evidence of corneal nerve damage.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.