Clinical trial Recruiting at 2 sites Interventional Ages 50 to 80

Isoinertial training for people with COPD

Official title: Effect of Isoinertial Training on Muscle Strength and Functional Capacity in Patients With Chronic Obstructive Pulmonary Disease (COPD): A Randomized Controlled Clinical Trial

Run by Universidad Manuela Beltrán · NCT07605117 · Data updated 2026-11-12

This study tests whether an isoinertial training program can improve muscle strength and functional capacity in adults with moderate to severe COPD.

Quick facts

Study typeInterventional
Ages50 Years to 80 Years
SexAll
Enrollment30 (estimated)
SponsorUniversidad Manuela Beltrán
Academic / other
Locations2 sites (Bogotá, Bogotá, DC and 1 other locations)
StatusRecruiting
StartedMay 7, 2026
Main results expectedJuly 25, 2026
Study endsJuly 27, 2026
Registry record updatedMay 29, 2026
Trial IDNCT07605117 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 50–80 with moderate to severe COPD who can safely participate in an exercise program and give informed consent.

Probably not a fit

Individuals with recent acute COPD exacerbations, significant comorbidities limiting exercise, or contraindications to exercise may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this randomized controlled trial, adults aged 50–80 with moderate to severe COPD will be assigned to either an isoinertial training program or continue with usual pulmonary rehabilitation for 8 weeks. The intervention uses an isoinertial device with progressive loads to strengthen upper and lower limbs, with sessions 2–3 times per week. Researchers will measure muscle strength, functional capacity, and clinical parameters at baseline and after the intervention. The study aims to determine if isoinertial training provides added benefits beyond standard rehabilitation. Enrollment targets 30 participants, with equal representation of men and women, across two sites in Colombia.

Why it matters

Potential benefit: If successful, participants may gain greater improvements in strength and daily functioning beyond standard rehabilitation.

How similar studies have gone: Previous work suggests that resistance-based training can benefit COPD patients; this study examines isoinertial training specifically.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* People between 50 - 80 years of age diagnosed with moderate or severe COPD
* No acute exacerbations in the last 4 weeks
* Sufficient functional capacity to exercise
* Signed informed consent

Exclusion Criteria:

* Presence of neurological, musculoskeletal, or cardiovascular diseases that significantly limit exercise performance or compromise participant safety; including uncontrolled hypertension, recent myocardial infarction, unstable angina, severe osteoarthritis, stroke sequelae, or Parkinson's disease.
* Contraindications to exercise participation according to medical evaluation.
* Recent surgeries in the past 3 months
* Simultaneous participation in other exercise programs
* Cognitive disorders

Where it's running

  • Universidad Manuela Beltrán
    Bogotá, Bogotá, DC, Colombia
    Recruiting
  • Pulsar Unidad de Neumologia y Rehabilitación Pulmonar
    Ibague, Ibagué, Colombia
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.