Isoinertial training for people with COPD
Official title: Effect of Isoinertial Training on Muscle Strength and Functional Capacity in Patients With Chronic Obstructive Pulmonary Disease (COPD): A Randomized Controlled Clinical Trial
Run by Universidad Manuela Beltrán · NCT07605117 · Data updated 2026-11-12
This study tests whether an isoinertial training program can improve muscle strength and functional capacity in adults with moderate to severe COPD.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 50 Years to 80 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Universidad Manuela Beltrán Academic / other |
| Locations | 2 sites (Bogotá, Bogotá, DC and 1 other locations) |
| Status | Recruiting |
| Started | May 7, 2026 |
| Main results expected | July 25, 2026 |
| Study ends | July 27, 2026 |
| Registry record updated | May 29, 2026 |
| Trial ID | NCT07605117 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 50–80 with moderate to severe COPD who can safely participate in an exercise program and give informed consent.
✕Probably not a fit
Individuals with recent acute COPD exacerbations, significant comorbidities limiting exercise, or contraindications to exercise may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In this randomized controlled trial, adults aged 50–80 with moderate to severe COPD will be assigned to either an isoinertial training program or continue with usual pulmonary rehabilitation for 8 weeks. The intervention uses an isoinertial device with progressive loads to strengthen upper and lower limbs, with sessions 2–3 times per week. Researchers will measure muscle strength, functional capacity, and clinical parameters at baseline and after the intervention. The study aims to determine if isoinertial training provides added benefits beyond standard rehabilitation. Enrollment targets 30 participants, with equal representation of men and women, across two sites in Colombia.
Why it matters
Potential benefit: If successful, participants may gain greater improvements in strength and daily functioning beyond standard rehabilitation.
How similar studies have gone: Previous work suggests that resistance-based training can benefit COPD patients; this study examines isoinertial training specifically.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * People between 50 - 80 years of age diagnosed with moderate or severe COPD * No acute exacerbations in the last 4 weeks * Sufficient functional capacity to exercise * Signed informed consent Exclusion Criteria: * Presence of neurological, musculoskeletal, or cardiovascular diseases that significantly limit exercise performance or compromise participant safety; including uncontrolled hypertension, recent myocardial infarction, unstable angina, severe osteoarthritis, stroke sequelae, or Parkinson's disease. * Contraindications to exercise participation according to medical evaluation. * Recent surgeries in the past 3 months * Simultaneous participation in other exercise programs * Cognitive disorders
Where it's running
-
Universidad Manuela Beltrán
Bogotá, Bogotá, DC, Colombia Recruiting -
Pulsar Unidad de Neumologia y Rehabilitación Pulmonar
Ibague, Ibagué, Colombia Recruiting
Study contacts
- Study coordinator: David Murcia-Lesmes, PhD
- Email: david.murcia@docentes.umb.edu.co
- Phone: +571 5460600
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.