Investigating how testosterone affects muscle growth and memory
Long-term Effects of Anabolic Androgenic Steroids on Muscle Growth Potential: Testosterone-induced Muscle Memory and Underlying Mechanisms
This study tests how testosterone affects muscle growth and memory in healthy people who are doing resistance training.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | Male |
| Sponsor | University of Copenhagen Academic / other |
| Locations | 1 site (Copenhagen) |
| Trial ID | NCT06188767 on ClinicalTrials.gov |
What this trial studies
This project aims to explore the mechanisms behind muscle hypertrophy and muscle memory induced by testosterone and resistance training in healthy individuals. Participants will receive testosterone undecanoate while their muscle physiology is monitored. The study will focus on understanding how testosterone influences muscle adaptation and retention of strength over time. By examining these effects, the research seeks to provide insights into optimizing muscle health and performance.
Who should consider this trial
Good fit: Ideal candidates are healthy men and women with a BMI under 26 and normal cardiovascular health.
Not a fit: Patients with chronic diseases, those who smoke, or individuals with a history of musculoskeletal injuries may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved strategies for enhancing muscle growth and recovery in various populations.
How similar studies have performed: While there have been studies on testosterone and muscle physiology, this specific investigation into muscle memory mechanisms is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy men and women * BMI of \<26 and normal ECG and blood pressure Exclusion Criteria: * Smoking * Chronic disease, * Use of prescription medication * Pain due to current or previous musculoskeletal injury * Resistance training more than once per week in the 12 months leading up to the intervention * Current or previous use of prohibited anabolic substances
Where this trial is running
Copenhagen
- The August Krogh Section for Human and Molecular Physiology, Department of Nutrition, Exercise and Sports, University of Copenhagen — Copenhagen, Denmark (Recruiting)
Study contacts
- Study coordinator: Lukas Moesgaard
- Email: lm@nexs.ku.dk
- Phone: +4561724440
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.