Investigating concussions and contact sports in patients with REM sleep behavior disorder

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the relationship between concussions, contact sports, and REM sleep behavior disorder (RBD). It will compare a group of patients diagnosed with RBD to a control group without RBD to determine the prevalence of concussions and exposure to contact sports in both groups. Participants will be interviewed by a sleep medicine specialist to gather detailed histories regarding their concussion experiences and contact sports involvement. The findings may provide insights into potential risk factors associated with neurodegenerative disorders linked to RBD.

Why it matters

Who can join: the full rules

Inclusion criteria group with RBD:

* Patient at the SDC with diagnosis of RBD (Guy's and St Thomas' NHS Foundation Trust).
* 50 years of age or above (patients below this age would not be expected to have a RBD related to a synucleinopathy and other causes of RBD would need to be considered instead - e.g. narcolepsy, post-traumatic stress disorder).

Inclusion criteria control group:

* Patients who have undergone a v-PSG at the SDC (Guy's and St Thomas' NHS Foundation Trust) and who do not have history of suspected RBD or RBD confirmed by v-PSG.
* 50 years of age or above This group will be age- and sex-matched to the RBD group.

Exclusion criteria group with RBD:

* Age \< 50 years of age.
* Diagnoses of narcolepsy or post-traumatic stress disorder.
* Subjects lacking capacity or literacy.
* Non-English speakers.

Exclusion criteria control group:

* Age \< 50 years of age (in order to match RBD group).
* REM sleep without atonia or confirmed RBD on v-PSG.
* Diagnosis of neurological diseases, cognitive complaints or motor complaints.
* Clinical history suggestive of parasomnia that may be included in the differential of RBD.
* Subjects lacking capacity or literacy.
* Non-English speakers.

Where it's running

• Guy's & St Thomas' NHS Foundation Trust
  London, London, United Kingdom Recruiting

Study contacts

• Study coordinator: Laura Pérez-Carbonell, PhD
• Email: laura.perezcarbonell@gstt.nhs.uk
• Phone: 02071883430

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.