Investigating Clostridium Difficile Infection in Infants
A Retrospective Cohort Study on the Epidemiological Characteristics and Biomarkers of Clostridium Difficile Infection in Infants
This study looks at how common Clostridium difficile infections are in infants and what factors might increase the risk, to help improve diagnosis and treatment for these young patients.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 0 Months to 24 Months |
| Sex | All |
| Sponsor | First People's Hospital of Hangzhou Academic / other |
| Locations | 1 site (Hangzhou, Zhejiang, China) |
| Trial ID | NCT06703918 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the epidemiological characteristics and biomarkers associated with Clostridium difficile infection (CDI) in infants. By analyzing historical medical data and patient questionnaires, the study will identify prevalence, risk factors, and unique biomarkers linked to CDI in pediatric patients. The objectives include evaluating demographic and clinical characteristics, assessing high-risk factors, and establishing baseline biomarkers to enhance diagnosis and treatment strategies for affected infants.
Who should consider this trial
Good fit: Ideal candidates for this study are infants aged 0-2 years with confirmed Clostridium difficile infection or without infection for comparison.
Not a fit: Patients older than 2 years or those with incomplete medical records or other severe gastrointestinal conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnosis and management of Clostridium difficile infection in infants.
How similar studies have performed: While this study focuses on a relatively rare infection in infants, similar epidemiological studies have shown success in identifying risk factors and biomarkers in other populations.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Infants ( aged 0-2 years). Medical records and patient questionnaires available with confirmed Clostridium difficile infection (for case group) or without infection (for control group). Exclusion Criteria: * Infants beyond the age of 2 years at the time of diagnosis. Incomplete medical records or missing essential information related to infection status, feeding methods, or antibiotic exposure.Patients with other severe gastrointestinal conditions that may confound results.
Where this trial is running
Hangzhou, Zhejiang, China
- Hangzhou First People's Hospital — Hangzhou, Zhejiang, China, China (Recruiting)
Study contacts
- Study coordinator: Li Qian Wang, Master of Medicine
- Email: wanglq921206@163.com
- Phone: 86+18768156110
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.