Fecal Transplant for Clostridioides difficile Infection
Official title: Fecal Microbiota Transplantation (FMT) for Recurrent Clostridium Difficile Infection - an Observational Cohort Study
Run by University of Aarhus · NCT03712722 · Data updated 2026-11-12
This project tests fecal microbiota transplantation for adults with Clostridioides difficile infection to see if it helps treat the illness.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 99 Years |
| Sex | All |
| Enrollment | 2000 (estimated) |
| Sponsor | University of Aarhus Academic / other |
| Locations | 1 site (Aarhus N) |
| Status | Recruiting |
| Started | October 1, 2018 |
| Main results expected | December 31, 2029 |
| Study ends | December 31, 2031 |
| Registry record updated | October 16, 2026 |
| Trial ID | NCT03712722 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 and older with documented Clostridioides difficile infection who are treated within AUH and affiliated hospitals.
✕Probably not a fit
Some patients may not experience symptom relief or could have complications related to the procedure.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational effort takes place within the Center for Fecal Microbiota Transplantation at Aarhus University Hospital. Patients with confirmed Clostridioides difficile infection are assessed, treated, and monitored as part of an integrated care project across AUH and affiliated hospitals. The study focuses on real-world use of fecal microbiota transplantation to understand safety, feasibility, and potential outcomes in routine clinical practice. No randomization or experimental design is described beyond observation of standard FMT procedures. The lead institution is Aarhus University, with care delivered at Aarhus University Hospital in Aarhus N and partner sites.
Why it matters
Potential benefit: If successful, patients may experience improved symptoms and resolution of infection following fecal microbiota transplantation.
How similar studies have gone: Previous experiences with FMT for CDI have shown symptom improvement in many patients, though this specific observational setup contributes real-world insights from AUH.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * age 18 or higher * documented Clostridioides difficile infection Exclusion Criteria: * none
Where it's running
-
Aarhus University Hospital
Aarhus N, Denmark Recruiting
Study contacts
- Study coordinator: Christian L Hvas, MD PhD
- Email: christian.hvas@auh.rm.dk
- Phone: +4528351839
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Using alanyl-glutamine to treat C. difficile infections
This study is testing if taking alanyl-glutamine can help people with C. difficile infections recover better and prevent the infection from coming back.
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Diet and counseling to see how meals affect gut health after CDI
We’re testing whether different meal plans and health counseling can influence the gut microbiome and reduce chances of CDI coming back in adults who are being treated for CDI.
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Lyophilized fecal microbiota transplant for adults with active ulcerative colitis
This trial will test whether a dried (lyophilized) fecal microbiota transplant helps adults with active ulcerative colitis when added to their current treatment or started alongside a new advanced medication.
-
How antibiotics versus fecal transplants affect recovery from C. difficile infection
This project will see how antibiotics and fecal microbiota transplant (FMT) affect adults with C. difficile infection by tracking recovery and biological changes over time.
-
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This will try a single dose of the antibody AZD5148 versus placebo to see if it prevents repeat C. difficile infections in adults being treated for a current infection.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.