Investigating chronic pain after cesarean section

Analysis of the Incidence and Risk Factors of Chronic Pain After Cesarean Section

Observational Huazhong University of Science and Technology · NCT06704490

This study looks at how many women experience ongoing pain after a cesarean section and how it might relate to postpartum depression and their overall quality of life.

Quick facts

Study typeObservational
Enrollment600 (estimated)
Ages20 Years to 50 Years
SexFemale
SponsorHuazhong University of Science and Technology Academic / other
Locations1 site (Wuhan, Hubei)
Trial IDNCT06704490 on ClinicalTrials.gov

What this trial studies

This observational study aims to prospectively assess the incidence and characteristics of persistent pain in women following cesarean section surgery at 3, 6, and 12 months post-operation. It will utilize regression analysis and data modeling to explore the relationship between various perioperative factors and the development of chronic pain. Additionally, the study will examine how chronic pain may correlate with postpartum depression, impacting the quality of life for new mothers.

Who should consider this trial

Good fit: Ideal candidates for this study are pregnant women aged 20 to 50 years who are scheduled for a planned cesarean section.

Not a fit: Patients with a history of dementia, mental illness, or central nervous system disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved management strategies for chronic pain after cesarean sections, enhancing the quality of life for postpartum women.

How similar studies have performed: While chronic postoperative pain is a recognized issue, this specific approach to studying its incidence and risk factors in postpartum women after cesarean sections is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age range from 20 to 50 years old;
* ASA grades I to III;
* Full term pregnancy and planned cesarean section with transverse incision in the lower segment of the uterus;
* Pregnant women who are willing to participate in this study and sign informed consent forms.

Exclusion Criteria:

* Have a history of dementia, mental illness, or any central nervous system disorder;
* Pregnant women who are addicted to alcohol and drugs;
* Difficulty in follow-up or poor patient compliance;
* Has taken other investigational drugs or participated in other clinical trials in the three months prior to being selected for the study;
* Serious complications occur during delivery;
* Unable to cooperate with the research for any reason.

Where this trial is running

Wuhan, Hubei

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Postoperative PainCesarean Section Surgerypostoperative painchronic postoperative paincesarean section surgeryPostpartum depression
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.