Intestinal ultrasound-guided management for inflammatory bowel disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial compares standard care alone to standard care plus intestinal ultrasound (IUS) performed at every visit in adults with inflammatory bowel disease. Patients undergoing endoscopy for disease assessment are assigned 1:1 to receive IUS in addition to routine care or to continue with standard care only, and are followed for 48 weeks with visits every 2 months if active disease and every 4 months if in remission. IUS measures bowel wall thickness, Doppler signal, and mesenteric fat, with ultrasound operators blinded to concurrent lab results. The primary outcome is the proportion of participants whose treatment changes during the follow-up period. The study is conducted at Siriraj Hospital, Mahidol University, with inclusion criteria focusing on adults with IBD and undergoing endoscopy, and excluding pregnancy, unstable conditions, distal disease only, or prior biologic failure.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of inflammatory bowel disease for more than 2 months
* Age 18 years or older
* Undergoing endoscopy at enrollment for assessment of disease severity

Exclusion Criteria:

* Pregnancy
* Unstable underlying medical conditions
* Inflammatory bowel disease limited to the distal rectum (within 10 cm of the anal verge) or perianal disease only
* Biologic failure

Where it's running

• Faculty of Medicine Siriraj Hospital, Mahidol University
  Bangkok, Thailand Recruiting

Study contacts

• Principal investigator: Julajak Limsrivilai, MD — Mahidol University
• Study coordinator: Thanaboon Chaemsupaphan, MD
• Email: ping_tnt@hotmail.com
• Phone: +66 86 896 4889

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.