International Headache Registry

International Headache and Vertigo Registration Study

Observational Second Affiliated Hospital, School of Medicine, Zhejiang University · NCT05418218

This study is collecting information from people aged 4 to 99 who have headaches or related conditions to see how these issues affect their health and treatment over time.

Quick facts

Study typeObservational
Enrollment200000 (estimated)
Ages4 Years to 99 Years
SexAll
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University Academic / other
Locations1 site (Hangzhou, Zhejiang)
Trial IDNCT05418218 on ClinicalTrials.gov

What this trial studies

The International Headache Registry collects data from patients aged 4 to 99 years who suffer from various headache disorders, including migraines and tension-type headaches, as well as vertigo and chronic pain conditions like fibromyalgia. This observational study aims to analyze biomarkers, imaging features, genetic characteristics, and treatment outcomes related to these conditions. Participants will undergo long-term follow-up to assess the progression and management of their symptoms. The study seeks to enhance understanding of headache-related diseases and their interconnections with other health issues.

Who should consider this trial

Good fit: Ideal candidates include individuals aged 4 to 99 years with diagnosed primary or secondary headache disorders, vertigo, or chronic pain.

Not a fit: Patients who are unable to complete headache diaries or who cannot participate in long-term follow-up may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnosis and treatment strategies for patients suffering from headache disorders and related conditions.

How similar studies have performed: Other studies focusing on headache disorders and their biomarkers have shown promise, indicating that this approach could yield valuable insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

The following are requirements for entry into the study:

1. Written informed consent and participant privacy information (eg, Written Authorization for Use and Release of Health and Research Study Information) obtained from the participant prior to initiation of any study-specific procedures.
2. Male or female participants ages 4 to 99 years, inclusive, at Visit 1.
3. Headache patients meeting the diagnostic criteria for ICHD-3, including primary headaches such as migraine and tension tension-type headaches, secondary headaches, and patients who meet the headache diagnosis in the ICHD-3 appendix (including vestibular migraine).

Exclusion Criteria:

1. Patients who were unable to complete scales such as headache diary.
2. Patients denied or unable to be admitted for long-term follow-up.

Where this trial is running

Hangzhou, Zhejiang

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Headache Disorders, PrimaryHeadache Disorders, SecondaryMigraineTension-Type HeadacheVertigoVestibular MigraineFibromyalgiaHeadache Disorders
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.