Clinical trial Recruiting at 1 site Observational Ages 4 to 99

International Headache Registry

Official title: International Headache and Vertigo Registration Study

Run by Second Affiliated Hospital, Zhejiang University, School of Medicine · NCT05418218 · Data updated 2026-11-12

This study is collecting information from people aged 4 to 99 who have headaches or related conditions to see how these issues affect their health and treatment over time.

Quick facts

Study typeObservational
Ages4 Years to 99 Years
SexAll
Enrollment200000 (estimated)
SponsorSecond Affiliated Hospital, Zhejiang University, School of Medicine
Academic / other
Locations1 site (Hangzhou, Zhejiang)
StatusRecruiting
StartedJuly 12, 2021
Main results expectedDecember 31, 2082
Study endsDecember 31, 2082
Registry record updatedMay 23, 2025
Trial IDNCT05418218 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals aged 4 to 99 years with diagnosed primary or secondary headache disorders, vertigo, or chronic pain.

Probably not a fit

Patients who are unable to complete headache diaries or who cannot participate in long-term follow-up may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The International Headache Registry collects data from patients aged 4 to 99 years who suffer from various headache disorders, including migraines and tension-type headaches, as well as vertigo and chronic pain conditions like fibromyalgia. This observational study aims to analyze biomarkers, imaging features, genetic characteristics, and treatment outcomes related to these conditions. Participants will undergo long-term follow-up to assess the progression and management of their symptoms. The study seeks to enhance understanding of headache-related diseases and their interconnections with other health issues.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnosis and treatment strategies for patients suffering from headache disorders and related conditions.

How similar studies have gone: Other studies focusing on headache disorders and their biomarkers have shown promise, indicating that this approach could yield valuable insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

The following are requirements for entry into the study:

1. Written informed consent and participant privacy information (eg, Written Authorization for Use and Release of Health and Research Study Information) obtained from the participant prior to initiation of any study-specific procedures.
2. Male or female participants ages 4 to 99 years, inclusive, at Visit 1.
3. Headache patients meeting the diagnostic criteria for ICHD-3, including primary headaches such as migraine and tension tension-type headaches, secondary headaches, and patients who meet the headache diagnosis in the ICHD-3 appendix (including vestibular migraine).

Exclusion Criteria:

1. Patients who were unable to complete scales such as headache diary.
2. Patients denied or unable to be admitted for long-term follow-up.

Where it's running

  • Kaiming Liu
    Hangzhou, Zhejiang, China
    Recruiting

Study contacts

  • Principal investigator: Kaiming Liu, Doctor — headache specialist clinic of the Second Affiliated Hospital of Zhejiang Medical University
  • Study coordinator: Kaiming Liu, Doctor
  • Email: 2314411@zju.edu.cn
  • Phone: +8615068862055

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.