Genetic and blood markers linked to Menière's disease and symptoms

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study enrolls adults with definite Menière's disease, a comparison group with vestibular migraine, and non-vestibular controls, primarily in an Italian (Caucasian) population. Researchers collect a blood sample for genetic testing of polymorphisms in genes involved in ionic homeostasis (for example KCNQ1 and KCNE1) and measure biohumoral markers. Genetic and blood-marker profiles will be compared across groups to look for correlations with clinical phenotypes such as episodic vertigo and fluctuating hearing loss. Participants who previously had ear surgery or intratympanic steroid or gentamicin therapy are excluded.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with definite Menière's Disease according to the criteria of the Barany Society

Exclusion Criteria:

* surgically treated before the examination or if they had undergone intratympanic therapy with steroids or gentamicin

Where it's running

• IRCCS San Raffaele
  Milan, Italy, Italy Recruiting

Study contacts

• Study coordinator: Roberto Carlo Teggi, MD
• Email: teggi.roberto@hsr.it
• Phone: +393921569410

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.