Increasing sleep duration to improve health in people with obesity

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to investigate the effects of extending sleep duration on plasma ceramides and insulin sensitivity in individuals with overweight and obesity who typically sleep less than 6.5 hours per night. Participants will be randomly assigned to either a sleep extension group, which will receive guidance to increase their nightly sleep by 2 hours, or a control group that will maintain their usual sleep habits while receiving basic health information. The intervention will last for 8 weeks, and both groups will be monitored for sleep duration and undergo laboratory assessments to evaluate metabolic changes. The study employs a randomized controlled design to ensure robust results.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age: 18-45 years old; equal numbers of men and women
2. Body mass index (BMI): 27.5-34.9 kg/m2
3. Sleep Habits: habitual self-reported average total sleep time (TST) \<6.5 hours per night for prior 6 months

Exclusion Criteria:

1. Clinically diagnosed sleep disorder or major psychiatric illness
2. Evidence of significant organ dysfunction or disease (e.g., heart disease, kidney disease)
3. Clinically diagnosed diabetes or fasting plasma glucose ≥126 mg/dL or HbA1c ≥6.5%
4. Use of prescription drugs or substances known to influence sleep or glucose metabolism, or anticoagulant medications.
5. Cancer that has been in remission less than 5 years
6. Pregnant/nursing, experiencing menopause or post-menopausal
7. Shift-work: current or history of within last year
8. Weight change: \>10% of body weight over prior six months
9. Current enrollment in weight loss or physical activity program like the Diabetes Prevention Program
10. Currently smoking
11. Alcohol intake\>14 drinks per week or \>3 drinks per day

Where it's running

• College of Health Research Complex--University of Utah
  Salt Lake City, Utah, United States Recruiting

Study contacts

• Study coordinator: Christopher M Depner, PhD
• Email: christopher.depner@utah.edu
• Phone: 801-581-2275

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.