Increasing Lung Cancer Screening for Smokers

Provider Support and Patient Outreach in Lung Cancer Screening

Not applicable Interventional Thomas Jefferson University · NCT05679349

This study is testing whether teaching doctors and patients about lung cancer screening can help more smokers get screened for the disease.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment822 (estimated)
Ages50 Years to 77 Years
SexAll
SponsorThomas Jefferson University Academic / other
Locations1 site (Philadelphia, Pennsylvania)
Trial IDNCT05679349 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of educational interventions aimed at increasing lung cancer screening among patients with a history of smoking. It involves randomizing healthcare providers and patients into different groups to assess the impact of education and shared decision-making on screening rates. The study also aims to identify factors that may facilitate or hinder the implementation of these interventions. By enhancing provider and patient knowledge about lung cancer screening, the trial seeks to improve early detection and treatment outcomes.

Who should consider this trial

Good fit: Ideal candidates are patients aged 50 to 77 with a significant smoking history who have an upcoming appointment with a primary care provider.

Not a fit: Patients who have had a recent lung computed tomography scan or do not meet the smoking history criteria may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to increased early detection of lung cancer, improving treatment outcomes for patients.

How similar studies have performed: Other studies have shown that educational interventions can successfully increase screening rates for various cancers, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* PRACTICE LEVEL:
* Primary care practice (family medicine, geriatrics, internal medicine) in one of the 4 participating health systems
* Practice using the main electronic medical record (EMR) of each system, in order to run appropriate patient recruitment reports
* Practice with at least 50% of practice providers (physicians and advanced care providers) consenting to participate
* PATIENT LEVEL:
* Have an office or telemedicine established patient visit scheduled with a primary care provider in one of the participating practices within next 14 to 25 days
* 50 to 77 years of age
* Have at least a 20-pack-year smoking history (based on self-report at baseline eligibility assessment)
* Currently smoke or have quit smoking within the past 15 years (based on self-report at baseline eligibility assessment)
* Able to communicate in English or Spanish (determined at baseline eligibility assessment)

Exclusion Criteria:

* PATIENT OUTREACH:
* Any lung computed tomography (CT) or low-dose computed tomography (LDCT) scan in the past 11 months, current procedural terminology (CPT) Codes are as follows

  * G0297 - LDCT screening
  * 71250 - CT w/o contrast
  * 71260 - CT w/ contrast
  * 71270 - CT with and w/o contrast
  * 71275 - CT angiography chest
  * 78815 - Positron emission tomography computed tomography (PET CT) skull base to mid-thigh
  * 78816 - PET CT whole body
* Prior history of lung cancer (The patient's problem list includes a problem with an international classification of diseases (ICD10) code of "Z85.118" or one beginning with "C34.", or by self-report at baseline eligibility assessment)
* Recent hospitalization (Admission date within the last 60 days listed in electronic health record (EHR), or by self-report at baseline eligibility assessment)
* Dementia (diagnosis codes F03.90 or F03.91) in EHR

Where this trial is running

Philadelphia, Pennsylvania

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Lung CarcinomaTobacco-Related Carcinoma
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.