Improving vision after brain injury

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial uses a double-blind, within-subject crossover design in adults with homonymous hemianopia from post-chiasmatic brain damage. Participants receive sessions of transcranial random noise stimulation (tRNS) paired with perceptual learning-based visual training and also receive sham stimulation in a separate period. Visual field measures and functional vision tasks are compared across the real and sham conditions to detect change. The design attempts to isolate the added effect of tRNS when combined with repeated training.

Why it matters

Who can join: the full rules

A. Stroke, brain tumor, or traumatic brain injury patients

Inclusion Criteria:

1. At least 18 years of age.
2. Capable of providing informed consent and complying with study procedures.
3. Unilateral or bilateral focal brain damage causing loss of vision.
4. At least three months post-stroke or traumatic brain injury, or a stable brain tumor within the past year.

Exclusion Criteria:

1. Severe CNS diseases or disorders unrelated to the focal lesion, which could interfere with study results.
2. Severe mental health challenges that could interfere with study results, or current or recent (within the past 6 months) drug or alcohol abuse or addiction as defined by DSM-5.
3. Vision loss resulting from ocular disease or disorder.

B. Healthy volunteers (age-matched controls):

Inclusion Criteria:

1. At least 18 years of age.
2. Capable of providing informed consent and complying with study procedures.

Exclusion Criteria:

1. Any CNS diseases or psychiatric disorders (e.g., epilepsy, schizophrenia) that would interfere with study results.
2. Previous head injury.
3. Present or past (within past 6 months) drug or alcohol abuse or addiction based on DSM-5.

Where it's running

• Georgetown University Medical Center
  Washington D.C., District of Columbia, United States Recruiting

Study contacts

• Study coordinator: Tina Liu, PhD
• Email: tina.liu@georgetown.edu
• Phone: 2027849920

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.