Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Home-based vision training guided by brain imaging

Official title: Behavioral Rehabilitation Through Image-Guided Home-based Training

Run by Georgetown University · NCT07635329 · Data updated 2026-11-12

This study tests whether at‑home, image-guided visual training can improve visual field function for adults with stroke-related vision loss.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment100 (estimated)
SponsorGeorgetown University
Academic / other
Locations1 site (Washington D.C., District of Columbia)
StatusRecruiting
StartedJuly 23, 2026
Main results expectedMarch 31, 2030
Study endsMarch 31, 2030
Registry record updatedSeptember 14, 2026
Trial IDNCT07635329 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18 and older with focal brain damage causing visual field loss, at least three months post-stroke or TBI or within the past year for a stable brain tumor, and eligible for MRI.

Probably not a fit

Individuals with severe unrelated neurological or psychiatric conditions, recent substance use disorders, or ocular diseases may not benefit from this training.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

BRIGHT uses a crossover design to combine visual testing, brain imaging, and home-based training to explore neural pathways of training-driven visual recovery. It compares high- and low-level perceptual training delivered remotely to see which helps improve visual performance. The study includes adults with unilateral or bilateral focal brain injury and visual field loss, who are eligible for MRI. Safety screening and informed consent are required before participation. The trial is led by Georgetown University with collaboration from the American Heart Association and is conducted at Georgetown University Medical Center.

Why it matters

Potential benefit: If successful, participants may experience improvements in visual field performance and quality of life from home-based training guided by brain imaging.

How similar studies have gone: Previous work in neuroplasticity and perceptual learning supports potential gains from vision training, though home-based, image-guided approaches are being explored in this setting.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. At least 18 years of age.
2. Capable of providing informed consent and complying with study procedures.
3. Unilateral or bilateral focal brain damage causing visual field loss.
4. At least three months post-stroke or traumatic brain injury, or a stable brain tumor within the past year.
5. Eligible for MRI based on standard safety screening.

Exclusion Criteria:

1. Severe neurological or psychiatric conditions unrelated to the focal lesion that may interfere with study participation or data interpretation.
2. Current or recent (within the past 6 months) drug or alcohol abuse or addiction as defined by DSM-5.
3. Ocular disease or disorder.

Where it's running

  • Georgetown University Medical Center
    Washington D.C., District of Columbia, United States
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.