Improving sleep to reduce alcohol use
Sleep as a Mechanism of Change in Alcohol Use Outcomes Among Heavy-Drinking Adults
This study is testing if treating insomnia can help people who drink heavily cut back on their alcohol use.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 256 (estimated) |
| Ages | 18 Years to 49 Years |
| Sex | All |
| Sponsor | University of Missouri-Columbia Academic / other |
| Locations | 1 site (Columbia, Missouri) |
| Trial ID | NCT06286774 on ClinicalTrials.gov |
What this trial studies
This project evaluates how improving insomnia can lead to better outcomes in alcohol use among individuals with heavy drinking habits. Participants who meet the criteria for both Alcohol Use Disorder and Insomnia Disorder will be randomly assigned to receive Cognitive Behavioral Therapy for Insomnia (CBT-I) or be placed on a waitlist control. The study will assess changes in insomnia and alcohol use outcomes weekly during treatment and at multiple follow-up points. The goal is to understand the relationship between insomnia treatment and reductions in alcohol consumption.
Who should consider this trial
Good fit: Ideal candidates are adults who engage in heavy drinking and also suffer from insomnia.
Not a fit: Patients over 50 years old or those with untreated moderate to severe sleep apnea may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could provide a novel pathway for reducing alcohol use by addressing insomnia.
How similar studies have performed: Other studies have shown promising results in using sleep interventions to improve alcohol use outcomes, indicating this approach has potential.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * report heavy drinking in a typical week in the past month * meet DSM-5 criteria for Alcohol Use Disorder * meet DSM-5 and research diagnostic criteria for Insomnia Disorder Exclusion Criteria: * ≥50 years * unable to provide informed consent * report contraindications for CBT-I (mania or seizure disorder) * moderate to severe sleep apnea that is untreated * have symptoms requiring immediate clinical attention (e.g., psychosis, suicide plan) * are already receiving behavioral treatment for insomnia or alcohol use
Where this trial is running
Columbia, Missouri
- University of Missouri-Columbia — Columbia, Missouri, United States (Recruiting)
Study contacts
- Study coordinator: Mary Beth Miller Miller, PhD
- Email: millmary@health.missouri.edu
- Phone: 573-882-1813
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.