Clinical trial Recruiting at 1 site Observational Ages 18 to 60

Insomnia and Sleep Disruption's Effect on Pain Sensitivity and Muscle Soreness After Exercise

Official title: The Impact of Insomnia on Pain Sensitivity and the Trajectory of Exercise Induced Muscular Pain: a Case Control Study

Run by The Hong Kong Polytechnic University · NCT07827664 · Data updated 2026-11-12

This study tests whether poor sleep or insomnia affects how people feel pain and recover from exercise-induced muscle soreness in healthy adults.

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Quick facts

Study typeObservational
Ages18 Years to 60 Years
SexAll
Enrollment80 (estimated)
SponsorThe Hong Kong Polytechnic University
Academic / other
Locations1 site (Hong Kong)
StatusRecruiting
StartedAugust 26, 2026
Main results expectedAugust 31, 2027
Study endsAugust 31, 2027
Registry record updatedSeptember 25, 2026
Trial IDNCT07827664 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are healthy adults aged 18–60 who are right-hand and right-foot dominant without chronic pain or sleep disorders other than insomnia.

Probably not a fit

Individuals with chronic musculoskeletal pain, sleep disorders other than insomnia, or contraindications to vigorous exercise may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will examine how sleep condition relates to pain sensitivity and the course of muscle soreness after a standardized eccentric exercise in healthy adults. Participants will undergo a safe, reversible pain model and will be evaluated for how sleep quality and duration influence pain responses over time. The study uses a single observational design to explore associations between sleep variables and pain dynamics in the general population. Results may help clarify whether sleep impacts pain perception and recovery after muscle stress.

Why it matters

Potential benefit: If successful, findings could inform strategies to minimize pain sensitivity and improve recovery through sleep-focused approaches.

How similar studies have gone: Previous research suggests sleep disruption can heighten pain sensitivity, but this study extends understanding in the general population using a controlled exercise-induced pain model.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 18 to 60 years
* Right hand and foot dominant

Exclusion Criteria:

* History of any chronic musculoskeletal pain or presence of existing pain during recruitment
* Previous major injuries or surgery involving the lower limbs
* Sleep disorders other than insomnia
* Clinically diagnosed psychiatric disorders
* Contraindications to vigorous exercise identified through the physical activity readiness questionnaire (PAR-Q)
* Work night shifts or rotating shift schedules
* Pregnant

Where it's running

  • the Hong Kong Polytechnic University
    Hong Kong, Hong Kong
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.