Improving pregnancy outcomes in women with PCOS using a new oocyte retrieval method

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to enhance pregnancy results for women with Polycystic Ovary Syndrome (PCOS) by utilizing a novel protocol for in vitro maturation (IVM) of oocytes. The approach includes the use of a Steiner-Tan needle for optimized oocyte retrieval, oral medications for priming, and delayed embryo transfer after cryopreservation. Participants will undergo a cycle of IVM following a regimen of oral contraceptives and letrozole, with oocyte retrieval timed for optimal maturity. The study seeks to assess the effectiveness of this method compared to existing literature on IVM outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* PCO pattern with \> 25 antral follicles
* AMH \> 3.5

Exclusion Criteria:

* BMI \> 35
* body morphology making transvaginal retrieval difficult or impossible
* complicating medical condition making pregnancy or IVF relatively contra-indicated

Where it's running

• Brown Fertility
  Jacksonville, Florida, United States Recruiting

Study contacts

• Principal investigator: Bruce I Rose, MD, PhD — Brown Fertility
• Study coordinator: Bruce I Rose, MD, PhD
• Email: brose@brownfertility.com
• Phone: 904-260-0352

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.