Integrated prenatal and postnatal treatment for newborns with critical congenital heart disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate an integrated treatment model for neonates with critical congenital heart disease (CCHD) that combines prenatal and postnatal care. The approach focuses on minimizing preoperative morbidities, optimizing the timing for surgical interventions, and enhancing postoperative outcomes compared to traditional care models. Additionally, the study investigates the potential for myocardial regeneration through early postnatal cardiac surgery in neonates with right cardiac system involvement. The ultimate goal is to improve diagnostic and therapeutic strategies for CCHD and enhance healthcare services for affected patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Full-term infants (gestational age 37-40 weeks): age less than 28 days;
2. Preterm infants (gestational age greater than 32 weeks but less than 37 weeks): corrected gestational age as neonatal period, age less than 28 days;
3. Birth weight \> 1.5 kg;
4. Fetal diagnosis of congenital heart diseases by ultrasound at 22-26 weeks of gestation, suitable for biventricular repair.

Exclusion Criteria:

1. Only suitable for palliative surgery or single ventricle repair;
2. Associated genetic/chromosomal abnormalities;
3. Associated with other severe systemic diseases.

Where it's running

• Biejing Anzhen Hospital
  Beijing, China Recruiting

Study contacts

• Study coordinator: Lizhi Lv, MD
• Email: prolvlizhi@126.com
• Phone: 86+ 18800167531

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.