Impact of Periodontal Inflammation on Allostatic Load

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study explores whether periodontal treatment can affect markers of allostatic load in adults with generalized periodontitis. Participants will receive subgingival instrumentation to reduce periodontal inflammation, and researchers will assess changes in biological stress markers and related health indicators. The goal is to clarify how oral inflammation relates to systemic stress and whether periodontal therapy can modulate this relationship. The study also considers how periodontitis staging and grading may relate to allostatic outcomes. Recruitment is limited to a specific geographic site in Rohtak, India.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with age group 30-50 years diagnosed with generalized periodontitis.
* Presence of minimum 20 teeth excluding third molars.

Exclusion Criteria:

* Periodontal treatment within last 6 months
* History of antibiotic use within the previous 3 months
* History of use of steroid, immunosuppressive and psychiatric drugs
* Pregnant and lactating women
* History of substance abuse

Where it's running

• Pgids
  Rohtak, Haryana, India Recruiting

Study contacts

• Study coordinator: Rajinder K Sharma, MDS
• Email: rksharmamds@yahoo.in
• Phone: +919416358222

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.