Impact of a 1-file rotary system on debris extrusion during root canal treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study examines the effect of a single-file AF One rotary system on apical debris extrusion during root canal preparation. The trial compares a flat-sided NiTi AF One file with conventional multi-step techniques to determine its impact on postoperative pain and cleaning efficacy. Eligible participants have mature teeth with either straight or mildly curved canals, intact crowns, and confirmed patency up to the apical foramen. Exclusion criteria include prior root canal treatment, resorption, immature apices, significant caries or fractures, and more than mild canal curvature. The study is conducted at Minia University Endodontics, focusing on standardized instrumentation, debris management, and clinical outcomes related to postoperative pain.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Teeth with mature apex
* Straight root canal or mild curvature not exceeding(5-10) Schneider.
* Has intact crown ( coronal structure)
* Presence of one orifices and one apices, patency achieved by a #10-15 K-file to the apical foramen

Exclusion Criteria:

* Previous root canal treatment.
* Internal/external resorption.
* Immature root apices.
* Caries/cracks/fractures on the root surface.
* Root canal curvature more than 10 degrees.
* Teeth in which the apical minor constriction was gauged larger than a size 20 hand file.

Where it's running

• Endodontics, Faculty of Dentistry, Minia University
  Minya, Minya Governorate, Egypt Recruiting

Study contacts

• Study coordinator: Nahla Nasr El-Din Fouad Mohamed, MSC
• Email: nannanasr248@gmail.com
• Phone: +201009067349

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• PECS II vs SPSIP nerve blocks for pain after mastectomy

  This study tests whether two ultrasound-guided nerve blocks (PECS II and SPSIP) differ in how much opioid patients need after mastectomy.

  Recruiting Bursa City Hospital · Nilufer, Bursa · NCT07929090

• Palatal Shield Technique to Reduce Pain and Improve Healing After Free Gingival Graft

  This randomized trial tests whether a collagen sponge with a protective palatal shield made of flowable resin helps reduce pain and improve healing after free gingival graft harvest.

  Recruiting Cairo University · Cairo, Cairo Governorate · NCT07926516

• Perfusion Index to Measure Postoperative Pain in Kids After Adenotonsillectomy

  This study tests whether the perfusion index can reliably reflect pain levels in children aged 1–12 after adenotonsillectomy, comparing standard care with an added glossopharyngeal nerve block.

  Recruiting Istanbul University · Istanbul, Istanbul · NCT07915804

• Anterior Knee Nerves Block vs Femoral Nerve Block for Knee Arthroscopy

  This trial tests whether an anterior nerves of the knee (ANK) block provides similar pain relief to a femoral nerve block after knee arthroscopy in adults, aiming to reduce quadriceps weakness.

  Recruiting Van Training and Research Hospital · Van · NCT07910500

• Natural Biopolymer-Based Irrigant for Root Canal Cleaning

  This trial tests a chitosan nanoparticle irrigant to improve cleaning and disinfection in single-rooted teeth with asymptomatic pulp necrosis undergoing endodontic treatment.

  Recruiting Minia University · Minya · NCT07901127

• Postoperative Pain Trajectories After Endometriosis Surgery

  This study tests how pain changes after endometriosis surgery and whether perioperative pain testing can predict who will have ongoing pain.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT07882498

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.