Imaging and analyzing blood clots in the brain
Official title: Thrombus Imaging and Treatment Analytics in Neurology
Run by Chinese PLA General Hospital · NCT05663281 · Data updated 2026-11-12
This study is testing how brain imaging of blood clots can help doctors understand treatment outcomes for patients with blocked arteries in the brain and neck.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Chinese PLA General Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Status | Recruiting |
| Started | December 15, 2022 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | July 3, 2024 |
| Trial ID | NCT05663281 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older with confirmed artery occlusions who can undergo high-resolution MR imaging.
✕Probably not a fit
Patients with mild to moderate artery stenosis, pregnant women, or those with prior stenting complications may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study utilizes high-resolution MR vessel wall imaging to examine patients with cerebral and cervical artery occlusions. The goal is to investigate how the appearance of thrombus on imaging correlates with the outcomes of recanalization treatments. By understanding these relationships, the study aims to address challenges in thrombus characteristics and improve prevention strategies for cerebrovascular diseases. Participants will undergo imaging to help identify potential biomarkers for arterial thrombophilia.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies and prevention methods for patients at risk of cerebrovascular diseases.
How similar studies have gone: Previous studies have shown promise in using imaging techniques to understand thrombus characteristics, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years * Extracranial and/or intracranial artery occlusion confirmed by angiography * Available for magnetic resonance high-resolution vessel wall imaging * Written informed consent obtained Exclusion Criteria: * Extracranial and/or intracranial artery mild to moderate stenosis * Pregnant women * Restenosis or occlusion after artery stenting placement
Where it's running
-
Chinese PLA General Hospital
Beijing, Beijing Municipality, China Recruiting
Study contacts
- Study coordinator: Jinhao Lyu, M.D.
- Email: 330322990@qq.com
- Phone: +8615903562929
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
GPIIb/IIIa PET/CT Imaging for Thrombi in the Brain and Body
This study tests an imaging tracer called 18F/68Ga-GP1 to see if it safely helps identify thrombi in adults who might have them.
-
Thromboelastometry to Predict Thrombosis and Survival in Glial Tumor Surgery
Aimed at people with glial tumors undergoing surgery, the study tests whether thromboelastometry and other blood tests can predict blood-clot risk and survival.
-
Personalized blood-thinner plan for leg artery disease after repair
A personalized plan using a blood test to tailor antiplatelet therapy is being tested against standard treatment in adults with PAD after a procedure to restore blood flow.
-
Multi-omics search for clotting and bleeding markers in coronary heart disease
This project will test whether combining proteins, metabolites, genes, sugar tags, and heart images can better predict clotting and major bleeding in people with coronary heart disease on dual antiplatelet therapy.
-
Gruticibart to Prevent Catheter-Related Blood Clots
This phase II trial tests whether a single dose of gruticibart can prevent blood clots caused by a central venous catheter in adults.
-
Apixaban vs Warfarin in HeartMate 3 LVAD Patients
This study tests whether apixaban can replace warfarin to prevent clots and bleeding problems in adults with an implanted HeartMate 3 LVAD for at least 3 months.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.