Clinical trial Recruiting at 1 site Observational Ages 18 and up

Imaging and analyzing blood clots in the brain

Official title: Thrombus Imaging and Treatment Analytics in Neurology

Run by Chinese PLA General Hospital · NCT05663281 · Data updated 2026-11-12

This study is testing how brain imaging of blood clots can help doctors understand treatment outcomes for patients with blocked arteries in the brain and neck.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment100 (estimated)
SponsorChinese PLA General Hospital
Academic / other
Locations1 site (Beijing, Beijing Municipality)
StatusRecruiting
StartedDecember 15, 2022
Main results expectedDecember 31, 2027
Study endsDecember 31, 2027
Registry record updatedJuly 3, 2024
Trial IDNCT05663281 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18 and older with confirmed artery occlusions who can undergo high-resolution MR imaging.

Probably not a fit

Patients with mild to moderate artery stenosis, pregnant women, or those with prior stenting complications may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study utilizes high-resolution MR vessel wall imaging to examine patients with cerebral and cervical artery occlusions. The goal is to investigate how the appearance of thrombus on imaging correlates with the outcomes of recanalization treatments. By understanding these relationships, the study aims to address challenges in thrombus characteristics and improve prevention strategies for cerebrovascular diseases. Participants will undergo imaging to help identify potential biomarkers for arterial thrombophilia.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment strategies and prevention methods for patients at risk of cerebrovascular diseases.

How similar studies have gone: Previous studies have shown promise in using imaging techniques to understand thrombus characteristics, suggesting potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* Extracranial and/or intracranial artery occlusion confirmed by angiography
* Available for magnetic resonance high-resolution vessel wall imaging
* Written informed consent obtained

Exclusion Criteria:

* Extracranial and/or intracranial artery mild to moderate stenosis
* Pregnant women
* Restenosis or occlusion after artery stenting placement

Where it's running

  • Chinese PLA General Hospital
    Beijing, Beijing Municipality, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • GPIIb/IIIa PET/CT Imaging for Thrombi in the Brain and Body

    This study tests an imaging tracer called 18F/68Ga-GP1 to see if it safely helps identify thrombi in adults who might have them.

    Recruiting at 3 sites Tianjin Medical University · Hefei, Anhui and 2 other locations · NCT07813559

  • Thromboelastometry to Predict Thrombosis and Survival in Glial Tumor Surgery

    Aimed at people with glial tumors undergoing surgery, the study tests whether thromboelastometry and other blood tests can predict blood-clot risk and survival.

    Recruiting Fundacion Clinic per a la Recerca Biomédica · Barcelona · NCT07813377

  • Personalized blood-thinner plan for leg artery disease after repair

    A personalized plan using a blood test to tailor antiplatelet therapy is being tested against standard treatment in adults with PAD after a procedure to restore blood flow.

    Recruiting at 2 sites Massachusetts General Hospital · Boston, Massachusetts and 1 other locations · NCT07613840

  • Multi-omics search for clotting and bleeding markers in coronary heart disease

    This project will test whether combining proteins, metabolites, genes, sugar tags, and heart images can better predict clotting and major bleeding in people with coronary heart disease on dual antiplatelet therapy.

    Recruiting at 3 sites Chinese Academy of Medical Sciences, Fuwai Hospital · Zhengzhou, Henan and 2 other locations · NCT07523880

  • Gruticibart to Prevent Catheter-Related Blood Clots

    This phase II trial tests whether a single dose of gruticibart can prevent blood clots caused by a central venous catheter in adults.

    Recruiting Phase 2 OHSU Knight Cancer Institute · Portland, Oregon · NCT07498517

  • Apixaban vs Warfarin in HeartMate 3 LVAD Patients

    This study tests whether apixaban can replace warfarin to prevent clots and bleeding problems in adults with an implanted HeartMate 3 LVAD for at least 3 months.

    Recruiting Phase 3 Columbia University · New York, New York · NCT07471139

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.