Newborn whole-genome sequencing and genetic disease risk in pregnancy and early life

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will enroll families during pregnancy or with newborn infants, obtain informed consent, and collect questionnaires and small biological samples at specified times. Samples may include peripheral blood, urine, and vaginal secretions and will undergo multi-omics processing such as nucleic acid extraction, sequencing, proteomics, metabolomics, and microbiome analysis. Generated genomic and other omics data will be stored in the hospital database and made available to approved investigators under review procedures. The project is an observational cohort designed to link genetic, environmental, and clinical data to maternal and child health outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Families with ongoing pregnancies (via assisted reproductive therap or natural conception) and newborn infants.

Exclusion Criteria:

* None

Where it's running

• Women's Hospital, School of Medicine, Zhejiang University
  Hangzhou, Zhejiang, China Recruiting

Study contacts

• Study coordinator: Hengchao Ruan, phD
• Email: ruanhengchao@zju.edu.cn
• Phone: 0571-88208964

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.