Identifying biomarkers for cognitive impairment after stroke using fNIRS

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to identify biomarkers associated with post-stroke cognitive impairment by utilizing functional near-infrared spectroscopy (fNIRS). It includes both healthy subjects and stroke patients, who will undergo cognitive tasks such as the Stroop task and verbal fluency tests while their brain activation is monitored. Various cognitive function assessments will be conducted to evaluate the participants' cognitive abilities and compare the results between the two groups. The goal is to uncover differences in brain activation and connectivity that may relate to cognitive decline following a stroke.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Stroke patients:

1. Diagnosis of stroke confirmed by neuroimaging (CT or MRI)
2. 18-80 years old
3. Able to complete the cognitive task
4. Able to follow instructions to complete the trial
5. Patients who signed an informed consent form.

Healthy Subjects:

1. No abnormalities on cranial
2. 18-80 years old
3. Able to complete cognitive task
4. Able to follow instructions to complete the trial
5. not taking medications.
6. Subjects who signed an informed consent form.

Exclusion Criteria:

Stroke patients:

1. Inability to tolerate the test due to organic diseases
2. Serious mental illness that prevents them from cooperating with or tolerating the trial
3. Pregnant or lactating women
4. Had metal implants, a history of other neurological disorders, acute cardiopulmonary dysfunction.

Healthy Subjects:

1. Inability to tolerate the test due to organic diseases
2. Serious mental illness that prevents them from cooperating with or tolerating the trial.
3. Pregnant or lactating women
4. Had metal implants, a history of other neurological disorders, acute cardiopulmonary dysfunction

Where it's running

• Department of Rehabilitation Medicine, the First Affiliated Hospital of Chongqing Medical University, Chongqing,
  Chongqing, Chongqing Municipality, China Recruiting

Study contacts

• Study coordinator: Dingqun Bai
• Email: baidingqun@hospital.cqmu.edu.cn
• Phone: 023-89011334

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Investigating brain activation in stroke patients using virtual reality tasks

  This study is testing how virtual reality tasks can help us understand brain activity in stroke patients compared to healthy people, to see if it can aid in their cognitive recovery.

  Recruiting First Affiliated Hospital of Chongqing Medical University · Chongqing, Chongqing Municipality · NCT06703320

• Using a polypill and lifestyle changes to prevent stroke and cognitive decline

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• Epigenetic risk factors for silent brain injury after TAVR in older adults

  This project will test whether blood epigenetic markers can predict new silent stroke-like brain lesions and later memory decline in people over 70 having TAVR.

  Recruiting University Hospital, Lille · Lille · NCT02972008

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.