Investigating brain activation in stroke patients using virtual reality tasks
Official title: Brain Activation Pattern Caused by Immersive Virtual Reality Pathfinding Task in Stroke Patients: a Functional Near-infrared Spectroscopy Study
Run by First Affiliated Hospital of Chongqing Medical University · NCT06703320 · Data updated 2026-11-12
This study is testing how virtual reality tasks can help us understand brain activity in stroke patients compared to healthy people, to see if it can aid in their cognitive recovery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | First Affiliated Hospital of Chongqing Medical University Academic / other |
| Locations | 1 site (Chongqing, Chongqing Municipality) |
| Status | Recruiting |
| Started | October 1, 2024 |
| Main results expected | April 1, 2025 |
| Study ends | April 30, 2025 |
| Registry record updated | November 26, 2024 |
| Trial ID | NCT06703320 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include stroke patients aged 18-80 who can complete cognitive tasks and follow instructions.
✕Probably not a fit
Patients with serious mental illnesses or those unable to tolerate the test due to organic diseases may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to explore brain activation patterns in stroke patients through an immersive virtual reality pathfinding task, utilizing functional near-infrared spectroscopy (fNIRS) for evaluation. Both stroke patients and healthy subjects aged 18-80 will participate, with cognitive function assessed using various standardized tests. The study will compare brain activation and connectivity between the two groups to better understand cognitive decline in stroke patients. This initial screening and preliminary intervention will provide insights into the cognitive rehabilitation potential of virtual reality.
Why it matters
Potential benefit: If successful, this study could enhance cognitive rehabilitation strategies for stroke patients.
How similar studies have gone: While the use of virtual reality in cognitive rehabilitation is gaining interest, this specific approach using fNIRS in stroke patients is relatively novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Stroke patients: 1. Diagnosis of stroke confirmed by neuroimaging (CT or MRI) 2. 18-80 years old 3. Able to complete the cognitive task 4. Able to follow instructions to complete the trial 5. Patients who signed an informed consent form. Healthy Subjects: 1. No abnormalities on cranial 2. 18-80 years old 3. Able to complete cognitive task 4. Able to follow instructions to complete the trial 5. not taking medications. 6. Subjects who signed an informed consent form. Exclusion Criteria: Stroke patients: 1. Inability to tolerate the test due to organic diseases 2. Serious mental illness that prevents them from cooperating with or tolerating the trial 3. Pregnant or lactating women 4. Had metal implants, a history of other neurological disorders, acute cardiopulmonary dysfunction. Healthy Subjects: 1. Inability to tolerate the test due to organic diseases 2. Serious mental illness that prevents them from cooperating with or tolerating the trial. 3. Pregnant or lactating women 4. Had metal implants, a history of other neurological disorders, acute cardiopulmonary dysfunction
Where it's running
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Department of Rehabilitation Medicine, the First Affiliated Hospital of Chongqing Medical University, Chongqing,, Chongqing, Chongqing 400010
Chongqing, Chongqing Municipality, China Recruiting
Study contacts
- Study coordinator: Dingqun Bai
- Email: baidingqun@hospital.cqmu.edu.cn
- Phone: 023-89011334
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.