Condition

Oral Squamous Cell Carcinoma (OSCC) clinical trials and research

• 6Clinical trials
• 3Countries

Newest Oral Squamous Cell Carcinoma (OSCC) clinical trials

All recruiting trials (6)

• TROP2-targeting NIR-II probe for real-time OSCC imaging during surgery

  This study tests whether applying a TTP-ICG imaging probe to freshly removed oral lesion tissue can help distinguish oral squamous cell carcinoma from benign conditions in real time.

  Recruiting Yunnan Cancer Hospital · Kunming, Yunnan · NCT07794813

• Shoulder-sparing neck surgery: comparing levels I-III vs I-IV in oral cancer with no neck nodes

  This trial tests whether removing lymph nodes only from levels I-III is as effective as extending to level IV for adults with oral squamous cell carcinoma that has no neck metastasis.

  Recruiting Kolhapur Cancer Centre - Cancer Centers of America · Kolhāpur, Maharashtra · NCT07726199

• Sintilimab with chemotherapy before and after surgery for locally advanced oral squamous cell carcinoma

  This trial will test whether adding sintilimab to chemotherapy before and after surgery helps people with locally advanced oral squamous cell carcinoma have fewer recurrences and better survival.

  Recruiting Phase 3 Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT07371611

• Hydrogen water oral care after free flap reconstruction for oral cancer

  A randomized trial tests whether hydrogen water oral care helps reduce inflammation and pain and improve oral bacteria after surgery for oral cancer.

  Recruiting Kaohsiung Medical University Chung-Ho Memorial Hospital · Kaohsiung City · NCT07306546

• Neoadjuvant immunochemotherapy to shrink advanced oral and oropharyngeal cancers before surgery

  This project tests two cycles of neoadjuvant immunochemotherapy (tislelizumab with paclitaxel plus cisplatin or carboplatin) in people with locally advanced oral or oropharyngeal squamous cell carcinoma to see tumor response and survival outcomes.

  Recruiting Zhujiang Hospital · Guangzhou, Guangdong · NCT07133958

• Comparing two surgical approaches for early mouth cancers

  This study is testing whether a less invasive surgery for early mouth cancers can provide similar survival rates while being easier on patients and more affordable than the standard approach.

  Recruiting Tata Memorial Hospital · Mumbai, Maharashtra and 2 other locations · NCT05774483

Related topics

Quick answers

How many Oral Squamous Cell Carcinoma (OSCC) clinical trials are recruiting right now?

6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in China (3 trials), India (2 trials), Taiwan (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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