Clinical trial Recruiting at 1 site Observational Ages 18 to 99

How chronic liver diseases connect with other long-term illnesses

Official title: The Association of Liver Disease With Other Systemic Diseases, Focus on Diseases Progression, Treatments, and Clinical Outcomes: Analyses From the Hospital Database of Buddhist Tzu Chi Medical Foundation

Run by Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation · NCT04525833 · Data updated 2026-11-12

We will look back at hospital records to see if chronic liver diseases are linked with other systemic illnesses in adults who visited Tzu Chi gastroenterology clinics.

Quick facts

Study typeObservational
Ages18 Years to 99 Years
SexAll
Enrollment15000 (estimated)
SponsorTaipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Academic / other
Locations1 site (New Taipei City)
StatusRecruiting
StartedJanuary 1, 2020
Main results expectedDecember 31, 2025
Study endsDecember 31, 2026
Registry record updatedSeptember 19, 2025
Trial IDNCT04525833 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–99 with medical records from gastroenterology clinics at the Tzu Chi hospitals, particularly those with recorded chronic liver disease, are the intended population.

Probably not a fit

People under 18 or over 99, those without records at Tzu Chi hospitals, or individuals seeking new interventional treatments rather than record-based insights are unlikely to receive direct benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a retrospective observational analysis of electronic health records from the Buddhist Tzu Chi Medical Foundation hospital database. The project will identify patients with chronic liver conditions (hepatitis B, hepatitis C, alcoholic liver disease, fatty liver, cirrhosis, and hepatocellular carcinoma) and examine associations with other systemic diseases, disease progression, treatments, and outcomes. Investigators will extract diagnoses, comorbidities, laboratory data, and treatment histories and apply statistical methods to detect correlations and patterns. Results aim to clarify how liver dysfunction influences risks and prognosis in other organ systems and to identify high-risk patient groups.

Why it matters

Potential benefit: If successful, this work could help clinicians identify patients at higher risk of systemic complications and improve monitoring or preventative care.

How similar studies have gone: Previous observational studies have reported links between diabetes and liver disease and between liver disease and systemic outcomes, but comprehensive retrospective analyses across multiple liver conditions are still limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Individuals who visited the gastroenterology clinics of the Tzu Chi Hospitals, Buddhist Tzu Chi Medical Foundation

Exclusion Criteria:

* Age younger than 18 or older than 99 years

Where it's running

  • Ching-Sheng Hsu
    New Taipei City, Taiwan
    Recruiting

Study contacts

  • Principal investigator: Ching-Sheng Hsu, Ph.D — Liver Diseases Research Center, Taipei Tzu Chi Hospital
  • Study coordinator: Ching-Sheng Hsu, Ph.D
  • Email: hsu.chingsheng@gmail.com
  • Phone: 886-979239381

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.