Collecting blood samples from healthy individuals and patients with cancer or benign diseases
Official title: Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer
Run by Helio Genomics · NCT05181826 · Data updated 2026-11-12
This study is collecting blood samples from healthy people and patients with cancer or non-cancer conditions to see if certain DNA markers can help detect cancer more accurately.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1200 (estimated) |
| Sponsor | Helio Genomics Industry-sponsored |
| Drugs / interventions | chemotherapy |
| Locations | 7 sites (Redondo Beach, California and 6 other locations) |
| Status | Recruiting |
| Started | May 21, 2019 |
| Main results expected | December 2027 |
| Study ends | January 2028 |
| Registry record updated | July 10, 2026 |
| Trial ID | NCT05181826 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older with a diagnosis of cancer, benign diseases, or those who are healthy volunteers.
✕Probably not a fit
Patients who are unwilling or unable to provide informed consent or have recently donated blood may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to collect blood samples from healthy volunteers, patients with active cancer, patients in remission, and those with benign diseases. The samples will be analyzed to evaluate the sensitivity and specificity of certain DNA methylation markers for cancer detection. Additionally, the study will investigate benign conditions that may lead to false results and assess the impact of substances like chemotherapy drugs on these markers. The goal is to enhance the understanding of cancer diagnostics and prognostics.
Why it matters
Potential benefit: If successful, this study could improve cancer detection methods and reduce false positives or negatives in diagnosis.
How similar studies have gone: Other studies have shown promise in using DNA methylation markers for cancer detection, indicating potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 2.1.1 Age 18 years or older. 2.1.2 A diagnosis of cancer, cancer remission, benign disease (benign tumor, diabetes, liver cirrhosis, chronic hepatitis B or hepatitis C virus infection, Chronic obstructive pulmonary disease, etc.) or apparently healthy volunteers. . Exclusion Criteria: 2.2.1 Patients that are unwilling or unable to sign the Informed Consent Form will be excluded. 2.2.2 Approximately 50 mL of blood will be drawn from participants within an 8-week period under this protocol. Patients that have already given 50 mL of blood within this time frame will be excluded.
Where it's running
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Allina Health, Virginia Piper Cancer Institute
Coon Rapids, Minnesota, United States Recruiting -
Virginia Piper Cancer Institute Mercy Hospital-Unity Campus
Fridley, Minnesota, United States Recruiting -
VPCI Oncology Research
Minneapolis, Minnesota, United States Recruiting -
Methodist LeBonheur Healthcare
Memphis, Tennessee, United States Recruiting -
Liver Center of Texas
Dallas, Texas, United States Recruiting -
Methodist Hospital
Richardson, Texas, United States Recruiting
Show 1 more location
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Torrance Memorial Physician Network - Cancer Care
Redondo Beach, California, United States Active not recruiting
Study contacts
- Study coordinator: Clinical Operations Manager
- Email: octavia@heliogenomics.com
- Phone: 6263500537
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.