Hospitalized adults with acute or chronic respiratory conditions: outcomes and recovery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational study enrolling adults admitted for acute respiratory conditions or followed in respiratory outpatient clinics for chronic lung disease, plus a healthy control group. It tracks short- and long-term outcomes over up to 36 months, including 30-day readmission, recovery, healthcare use, and mortality. Data are collected during hospitalization or within 90 days of follow-up, with optional follow-up visits and annual assessments. Follow-up can be by phone or in person, and visits may occur up to 90 days apart within predefined windows.

Why it matters

Who can join: the full rules

Inclusion Criteria (Core study participants)

1. Hospital admission with an acute respiratory diagnosis, or currently under the care of hospital respiratory outpatient services for a chronic respiratory disease
2. Participant is willing \& able to give informed consent for participation in the study
3. Aged 18 years or above
4. Able (in the Investigators opinion) \& willing to comply with all study requirements

Exclusion Criteria (Core study participants)

1. Unstable or life-threatening cardiac disease including myocardial infarction or unstable angina during current admission.
2. Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study.
3. Known pregnancy

Inclusion Criteria (Healthy Controls)

1. Aged 18 years or above
2. No underlying respiratory disease as self-reported
3. Able (in the Investigators opinion) \& willing to comply with all study requirements

Exclusion Criteria (Healthy Controls)

1. Hospitalised due to an acute respiratory illness in the last 6 weeks prior to consent
2. Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study.
3. Known pregnancy

Additional inclusion and exclusion criteria for CHESTY sub-studies are detailed in the corresponding sub-study protocols.

Where it's running

• Glenfield Hospital
  Leicester, United Kingdom Recruiting

Study contacts

• Principal investigator: Neil Greening, PhD, MRCP — NIHR Respiratory Biomedical Research Centre, Leicester
• Study coordinator: Jill Clanchy
• Email: chesty-catalina@leicester.ac.uk
• Phone: +44 (0)116 258 3370

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.