Home IOP telemonitoring with smartphone support for open-angle glaucoma

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this 30-month, multicenter study, 142 adults with newly diagnosed primary open-angle glaucoma are randomized to either home IOP telemonitoring with a smartphone intervention or standard smartphone-based care. Primary outcome is clinic-based Goldmann applanation tonometry IOP measurements collected every 3 months; secondary outcomes include rates of retinal nerve fiber layer thinning. The two groups receive similar targets for lowering IOP based on disease severity, with intent-to-treat analysis and consideration of both eyes when eligible. Participants must meet inclusion criteria such as adequate visual acuity and absence of major exclusion factors like very high IOP or prior complicated eye surgery. The study is led by The University of Hong Kong with Icare Finland Oy as a collaborator at the HKU Eye Centre.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Newly diagnosed primary open-angle glaucoma (POAG)
* Best corrected visual acuity (VA) ≥20/40 for the included eye(s)

Exclusion Criteria:

* IOP \>35 millimeters of mercury (mmHg)
* Dry eye syndrome
* Central corneal thickness \<500μm or \>600μm
* Failure to complete the iCare Home certification procedure at the baseline visits
* Only one eye with functional vision
* Inability to perform reliable visual field (VF)
* Pathological myopia (eyes with axial length≥26mm with lacquer cracks and chorioretinal atrophy)
* Suboptimal quality of optical coherence tomography (OCT) images (described below in RNFL imaging)
* Previous intraocular surgery or corneal refractive surgery other than uncomplicated cataract extraction
* Diabetic retinopathy/maculopathy

Where it's running

• HKU Eye Centre
  Wong Chuk Hang, Hong Kong Recruiting

Study contacts

• Principal investigator: Christopher Leung — The University of Hong Kong
• Study coordinator: Christopher Leung
• Email: cleung21@hku.hk
• Phone: 39102673

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Direct selective laser trabeculoplasty to lower eye pressure in untreated open-angle glaucoma

  This study will try direct selective laser trabeculoplasty (DSLT) to lower eye pressure by more than 20% without glaucoma medications over six months in adults newly diagnosed with open-angle glaucoma or ocular hypertension.

  Recruiting Shafer Vision Institute · Plymouth Meeting, Pennsylvania · NCT07076303

• Electrical stimulation treatment for visual field defects in glaucoma patients

  This study is testing if a new electrical stimulation treatment can help people with glaucoma keep their vision from getting worse while they continue using their regular eye drops.

  Recruiting Okuvision GmbH · Mainz · NCT06682962

• Assessing the Glycocalyx in Patients with Primary Open-angle Glaucoma

  This study is testing a special imaging technique to see if the tiny blood vessels in people with primary open-angle glaucoma are working properly compared to those without eye problems.

  Recruiting Fondation Ophtalmologique Adolphe de Rothschild · Paris · NCT05264818

• Balance training for people with glaucoma

  A randomized study tests whether a structured eight-week balance program helps adults with glaucoma improve balance, reduce fall risk, and lessen fear of falling.

  Recruiting Kanuni Sultan Suleyman Training and Research Hospital · Küçükçekmece, Istanbul · NCT07910955

• Eye drops Rhopressa vs Timolol to protect nerve cells in glaucoma

  In adults with open-angle glaucoma, this study tests whether Rhopressa helps preserve retinal nerve cells better than Timolol while both lower eye pressure.

  Recruiting Phase 4 Indiana University · Bloomington, Indiana · NCT07847073

• Comparison of FT-1000 non-contact tonometry with Goldmann applanation tonometry in glaucoma patients

  This study tests whether the FT-1000 non-contact tonometer gives measurements that agree with the Goldmann applanation tonometer in adults with glaucoma.

  Recruiting Tomey Corporation · Jacksonville, Florida · NCT07804277

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.