Taining Golden Lake comprehensive chronic disease management program

Taining Golden Lake Comprehensive Chronic Disease Management Initiative

This project will build a large cohort of adults in Taining County to collect health data and try to create a county-level chronic disease management model for people with hypertension, diabetes, dyslipidemia, and other long-term conditions.

Quick facts

• Study type: Observational
• Enrollment: 20000 (estimated)
• Ages: 18 Years and up
• Sex: All
• Sponsor: First Affiliated Hospital of Fujian Medical University (other)
• Locations: 1 site (Fuzhou, Fujian)
• Trial ID: NCT07308314 on ClinicalTrials.gov

What this trial studies

The project will enroll at least 20,000 residents aged 18 and older in Taining County and collect questionnaires, physical measurements, laboratory tests, imaging, and biological samples to form a multi-dimensional health database and biobank. Participants will undergo annual active follow-up for three years, supplemented by passive follow-up through local healthcare records and death registries. The study aims to describe epidemiological patterns and risk factors for common chronic diseases, map trajectories of multimorbidity and aging syndromes, and develop a replicable county-level chronic disease management model suited to rural, mountainous areas.

Who should consider this trial

Good fit: Ideal participants are adults (≥18 years) who have lived in Taining County for at least six months, can give informed consent, can complete baseline and follow-up visits, and expect to remain in the county for the next three years.

Not a fit: People with end-stage disease and expected survival under one year, severe cognitive or psychiatric impairment preventing participation, or long-term migrants unable to guarantee follow-up are unlikely to benefit from participation.

Why it matters

Potential benefit: If successful, this work could enable earlier detection and standardized, locally adapted management of chronic diseases that reduces complications and improves health outcomes in similar rural regions.

How similar studies have performed: Large population cohorts in China and internationally (for example the China Kadoorie Biobank) have successfully identified chronic disease risk factors, but implementing and validating a county-level chronic disease management model in a mountainous rural setting is relatively novel.

Eligibility criteria

Inclusion Criteria:

* Age ≥18 years, male or female.
* Resident of Taining County for ≥6 months and expected to remain in the county for at least the next 3 years.
* Full civil capacity and able to understand study procedures.
* Willing to voluntarily participate and provide written informed consent.
* Able to complete baseline survey and follow-up visits.

Exclusion Criteria:

* Refusal to sign informed consent.
* Severe psychiatric disorders or cognitive impairment preventing participation.
* End-stage disease with expected survival \<1 year.
* Long-term migrants (≥6 months per year outside the county), unable to guarantee follow-up.
* Participation in other clinical studies that may interfere with this research.

Where this trial is running

Fuzhou, Fujian

• The First Affiliated Hospital of Fujian Medical University — Fuzhou, Fujian, China (RECRUITING)

Study contacts

• Principal investigator: Dajun Chai, MD — First Affiliated Hospital of Fujian Medical University
• Study coordinator: Dajun Chai, MD

Conditions: Chronic Disease, Chronic Disease Management, Hypertension, Diabetes Mellitus, Dyslipidemias, Frailty, Sarcopenia, Prospective Cohort