Ultrasound-Guided PRP Injections for Nerve Regeneration in Traumatic Peripheral Nerve Injury

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective study compares ultrasound-guided PRP injections plus rehabilitation to conservative management in patients with traumatic peripheral nerve injury. It is non-randomized and uses a control cohort that does not receive PRP. Eligible participants are 18–45 years old with clinical evidence of injury, electrophysiological confirmation, ultrasound findings, and stable deficits for at least four weeks. The intervention consists of US-guided PRP injections and a rehabilitation program, with outcomes focused on nerve regeneration and functional recovery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Inclusion Criteria

Age 18 -45 years Clinical evidence of peripheral nerve injury Electrophysiological confirmation by nerve conduction studies (NCS) Ultrasound evidence of complete or partial continuity, neuroma, or entrapment Stable neurological deficit for at least 4 weeks prior to enrollment.

Exclusion Criteria:

* Complete nerve transection without surgical repair Active infection Coagulopathy or platelet disorders Prior regenerative injection therapy to the affected nerve.

Where it's running

• AL zahraa university hospital
  Cairo, Abbasia, Egypt Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• High-Intensity Peripheral Magnetic Stimulation for Traumatic Nerve Injury

  This study tests whether adding high-intensity peripheral magnetic stimulation to a structured exercise program can reduce pain and improve function for adults with a traumatic peripheral nerve injury.

  Recruiting Gaziler Physical Medicine and Rehabilitation Education and Research Hospital · Ankara · NCT07705490

• Digital versus traditional ankle-foot orthoses for people with lower limb weakness

  We will try if ankle-foot braces made with 3D scanning and printing work as well as traditional plaster-cast braces for people with leg weakness or stiffness from conditions like stroke or cerebral palsy.

  Recruiting Holland Bloorview Kids Rehabilitation Hospital · Mississauga, Ontario and 1 other locations · NCT06828653

• Transabdominal vs. Transvaginal Ultrasound in high-risk pregnancies during early weeks

  This study tests whether transabdominal ultrasound can visualize fetal structures as well as transvaginal ultrasound in high-risk singleton pregnancies between 9 and 13+6 weeks.

  Recruiting Al-Azhar University · Asyut · NCT07883850

• Dual Trigger vs HCG Trigger for Final Maturation in Normal Responders

  In normal responders undergoing ICSI cycles, this study tests whether using a dual trigger (GnRH agonist plus hCG) improves outcomes compared with the standard hCG trigger.

  Recruiting Al-Azhar University · Cairo, Cairo Governorate · NCT07861399

• Criteria-based Rehabilitation After Tibial Fracture Fixation

  This trial tests a structured, criteria-driven rehabilitation plan against usual physiotherapy after tibial fracture surgery to see if it improves leg function.

  Recruiting Al-Azhar University · Gaza, Gaza Strip · NCT07810478

• Sexual function and quality of life in monogamous vs polygamous marriages among Egyptian men

  This is a web-based survey to see if marital structure affects erectile function and sexual quality of life in Egyptian men who are married.

  Recruiting Al-Azhar University · Cairo · NCT07783958

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.