Helping smokers quit before surgery
Preoperative Smoking Cessation Program in Patients Undergoing Intermediate to High-risk Surgery: a Randomized, Single-blinded, Controlled Trial
This study is testing a strong program to help smokers quit before surgery to see if it can reduce problems after the operation.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 251 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Luzerner Kantonsspital Academic / other |
| Locations | 1 site (Luzern) |
| Trial ID | NCT05192837 on ClinicalTrials.gov |
What this trial studies
This study focuses on implementing a high-intensity smoking cessation program for patients scheduled for intermediate to high-risk surgeries. It aims to analyze the impact of this preoperative intervention on reducing postoperative complications within a 90-day period. The program targets current smokers who are motivated to quit, leveraging their surgical situation as a unique opportunity for cessation. The study will be conducted at the Kantonsspital of Lucerne, involving various surgical departments.
Who should consider this trial
Good fit: Ideal candidates are current smokers over 18 years old who are scheduled for intermediate or high-risk surgeries at the Kantonsspital of Lucerne.
Not a fit: Patients undergoing plastic surgery or those with alcohol dependency or severe psychological disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could significantly reduce postoperative complications and healthcare costs for smokers undergoing surgery.
How similar studies have performed: Previous studies have shown that preoperative smoking cessation interventions can lead to improved surgical outcomes, indicating a promising approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient listed for intermediate or high-risk surgery at the Kantonsspital of Lucerne * Patient undergoing surgery in one of the following departments: Abdominal surgery, thoracic surgery, cardiac surgery, urology, gynaecology, vascular surgery or head and neck surgery * Date of surgery \>2 weeks after date of listing for surgery or discussion by tumor board * Current smokers, defined as daily smoking of at least one cigarette, cigar or pipe * Age over 18 years * Able to give signed written informed consent Exclusion Criteria: * Plastic surgery * Consumption of illegal drugs * Alcohol dependency defined as preexisting alcohol related disorders (eg. alcoholic psychosis, Alcohol abuse, Alcohol polyneuropathy, degeneration of nervous system due to alcohol, Alcoholic myopathy, Alcoholic liver disease) * Inability to follow the procedures of the study, e.g., due to language problems, psychological disorders, dementia
Where this trial is running
Luzern
- Luks — Luzern, Switzerland (Recruiting)
Study contacts
- Principal investigator: Christian Fankhauser, PD Dr. med. — Klinik für Urologie, Luzerner Kantonsspital
- Study coordinator: Studienkoordination Tumorzentrum
- Email: studienkoordination.tumorzentrum@luks.ch
- Phone: 0041 41 205 59 64
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.