cancer Clinical Trials and Research
Also known as: malignancy, tumor, neoplasm, carcinoma, sarcoma, leukemia · ICD-10: C00-C96
Cancer is a group of diseases characterized by the uncontrolled growth and spread of abnormal cells. Clinical trial research focuses on developing new therapies, improving early detection, and enhancing patient quality of life. Find a Trial helps patients and caregivers search for active cancer studies.
Common questions about cancer clinical trials
Who can participate in cancer clinical trials?
Eligibility criteria vary by study, often including cancer type, stage, prior treatments, and overall health. These criteria help ensure patient safety and that researchers can effectively evaluate the study's intervention. Information is available on ClinicalTrials.gov.
What are the different phases of cancer clinical trials?
Cancer clinical trials typically progress through phases 1, 2, and 3. Phase 1 studies assess safety, phase 2 evaluates effectiveness and side effects, and phase 3 compares new treatments to standard ones. Data from ClinicalTrials.gov informs these stages.
Do cancer clinical trials cost money to participate?
Generally, study-related medical costs, such as experimental drugs and tests, are covered by the trial sponsor. However, routine medical care costs and other expenses like travel may be the participant's responsibility or covered by insurance. Details are specific to each study.
What are current research directions in cancer clinical trials?
Current research directions include immunotherapy, targeted therapies, precision medicine, and advanced radiation techniques. Studies also explore new surgical approaches, supportive care, and methods for early detection and prevention. This information is often found on ClinicalTrials.gov and NIH RePORTER.
What types of interventions are studied in cancer clinical trials?
Interventions in cancer trials can include new drugs, biologics, radiation therapies, surgical procedures, and combinations of treatments. Researchers also study behavioral interventions, dietary changes, and devices aimed at improving diagnosis or quality of life. Data is available on ClinicalTrials.gov.
Why are biomarkers important in cancer clinical trials?
Biomarkers, such as specific genes or proteins, help identify patients who might respond best to certain targeted therapies. They can also predict disease progression or recurrence, guiding personalized treatment strategies in clinical research. Information is often detailed on ClinicalTrials.gov and NIH RePORTER.
What are common reasons someone might not be eligible for a cancer trial?
Common exclusion criteria can include certain prior treatments, other serious medical conditions, or specific cancer stages that don't match the study's focus. These criteria help ensure patient safety and the scientific integrity of the research. Details are on ClinicalTrials.gov.
Are there cancer trials focused on improving quality of life?
Yes, many cancer trials focus on supportive care, symptom management, and improving patients' overall quality of life. These studies explore ways to reduce treatment side effects, manage pain, and address emotional and physical well-being. Such research is listed on ClinicalTrials.gov and NIH RePORTER.
How to find a cancer trial that fits you
- Describe your cancer situation in detail — stage if applicable, prior treatments, age, and other relevant conditions.
- Use the location filter (worldwide, US, US & Canada, Europe) to narrow to trials near you.
- Review each trial's eligibility criteria carefully. Save 2–5 candidates with their NCT numbers.
- Discuss with your treating clinician before contacting the research site.