Graftless Periosteal Coverage vs Xenogenic Graft for Jumping Gap in Immediate Mandibular Molar Implants
Official title: Graftless Periosteal Coverage Versus Xenogenic Bone Graft Beneath a Collagen Membrane for Jumping Gap Management in Immediate Mandibular Molar Implants: A Randomized Controlled Clinical and Radiographic Trial.
Run by Horus University · NCT07880184 · Data updated 2026-11-12
This study tests whether graftless periosteal coverage can perform as well as a xenogenic bone graft beneath a collagen membrane for managing a jumping gap in immediate mandibular molar implants.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 60 Years |
| Sex | All |
| Enrollment | 56 (estimated) |
| Sponsor | Horus University Academic / other |
| Locations | 3 sites (Al Mansurah, Dakahlia Governorate and 2 other locations) |
| Status | Recruiting |
| Started | March 31, 2026 |
| Main results expected | September 30, 2026 |
| Study ends | October 20, 2026 |
| Registry record updated | October 19, 2026 |
| Trial ID | NCT07880184 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults requiring a single mandibular molar immediate implant with a jumping gap ≥ 2 mm and adequate primary stability (≥ 30 Ncm), without uncontrolled systemic disease or other high-risk factors.
✕Probably not a fit
Patients with poor oral hygiene, smoking, uncontrolled systemic conditions, active infection, or severely parafunctional habits may not benefit from this approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective, parallel-arm, randomized controlled trial compares graftless periosteal coverage to a particulate xenogenic bone graft with a collagen membrane for managing jumping gaps beneath immediate mandibular molar implants. Primary outcomes include volumetric and bone density analyses at around 4 months. Secondary outcomes assess aesthetic results and implant stability. Participants must have a single mandibular molar needing immediate implant placement with a jumping gap of at least 2 mm and adequate initial implant stability, and must meet safety criteria.
Why it matters
Potential benefit: If successful, the graftless approach could simplify procedures and reduce graft material needs while maintaining bone and aesthetic outcomes.
How similar studies have gone: Prior studies in similar contexts have shown mixed or favorable results; this trial tests a graftless method against a standard xenogenic graft under a collagen membrane.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Single mandibular molar immediate implant placement, with an intraoperative jumping gap ≥ 2 mm, and adequate primary implant stability (≥30 Ncm). Exclusion Criteria: * Uncontrolled systemic diseases (e.g., uncontrolled diabetes), smokers, acute infection at the site, immunosuppressive therapy, severe parafunction, or poor oral hygiene (PI \> 25%).
Where it's running
-
Dental hospital of Aswan University
Aswān, Egypt Recruiting -
Faculty of Dentistry, Horus University, Egypt
Al Mansurah, Dakahlia Governorate, Egypt Completed -
Faculty of Dentistry, Mansoura University, Egypt
Al Mansurah, Dakahlia Governorate, Egypt Completed
Study contacts
- Study coordinator: Eman Abdel-Salam, Associate Prof
- Email: moonysalam1302@gmail.com
- Phone: +201556767533
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.