Comparing two bone grafts to preserve the socket after tooth extraction
Official title: Comparative Analysis of Healing Outcomes Between Two Bone Graft Materials in Socket Preservation Procedure
Run by Pharos University in Alexandria · NCT07344025 · Data updated 2026-11-12
This test will compare an allograft and a bovine xenograft to see which better preserves jaw bone and gum shape after tooth extraction in healthy adults aged 21–50.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 21 Years to 50 Years |
| Sex | All |
| Enrollment | 18 (estimated) |
| Sponsor | Pharos University in Alexandria Academic / other |
| Locations | 1 site (Alexandria) |
| Status | Recruiting |
| Started | January 2026 |
| Main results expected | January 2026 |
| Study ends | April 2026 |
| Registry record updated | January 20, 2026 |
| Trial ID | NCT07344025 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Healthy, non-smoking adults aged 21–50 who need tooth extraction and socket preservation, have good oral hygiene, and no conditions or medications affecting bone metabolism.
✕Probably not a fit
Patients with advanced periodontitis, active infection, severely resorbed sockets (buccal bone height <5 mm), heavy smokers, pregnant patients, or those on bone‑affecting medications are unlikely to qualify or benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Patients needing socket preservation after tooth extraction will be recruited from the Pharos University College of Dentistry outpatient clinic and must be systemically healthy non-smokers with good oral hygiene. Preoperative CBCT scans and fabricated reference stents will provide standardized baseline measurements of bone dimensions. Socket preservation procedures will be performed under local anesthesia using either an allograft or a bovine xenograft, with clinical measurements and histologic samples collected after 2–3 months of healing. Outcomes will compare dimensional bone changes and histologic bone formation between the two graft materials.
Why it matters
Potential benefit: If successful, the better-performing graft could help maintain bone and gum contours after extraction, making future implant placement easier and more predictable.
How similar studies have gone: Previous research shows both allografts and bovine xenografts can help preserve ridge dimensions, but direct head‑to‑head comparisons yield variable results.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * • Systemically healthy individuals * Non-smokers * Age between 21 and 50 years * Indicated for tooth extraction and socket preservation * Good oral hygiene (full-mouth plaque score \<20%) * Willingness to participate and provide informed consent Exclusion Criteria: * • Stage III or IV periodontitis * Active periodontal or periapical infection * Severely resorbed sockets (buccal bone height \<5 mm) * Smoking more than 10 cigarettes per day * Pregnancy * Systemic conditions or medications affecting bone metabolism
Where it's running
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College of Dentistry, Pharos University
Alexandria, Egypt Recruiting
Study contacts
- Principal investigator: H Sakr, PhD — Pharos university
- Study coordinator: Haitham Sakr, PhD
- Email: haitham.sakr@pua.edu.eg
- Phone: 3877700
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.