Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Single crowns on narrow versus standard implants for missing molar teeth

Official title: Single Implant Crowns Supported by Narrow or Standard Diameter Implants in Molar Sites: a Randomized Controlled Trial

Run by Mohammed Bin Rashid University of Medicine and Health Sciences · NCT07073196 · Data updated 2026-11-12

This trial will test whether narrow titanium‑zirconium implants work as well as standard implants to replace a single missing molar in adults with limited horizontal bone width.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment40 (estimated)
SponsorMohammed Bin Rashid University of Medicine and Health Sciences
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Dubai)
StatusRecruiting
StartedOctober 1, 2025
Main results expectedFebruary 1, 2028
Study endsDecember 1, 2029
Registry record updatedJuly 18, 2025
Trial IDNCT07073196 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (≥18 years) with a single missing molar in a fully healed site (≥6 months), limited horizontal bone width (≤6 mm) and at least 8 mm height, good oral hygiene, intact adjacent and opposing teeth, and willingness to attend follow‑up visits are ideal candidates.

Probably not a fit

Patients with active or generalized periodontitis, bone metabolic disease or medications affecting bone, smokers, severe bruxism, recent malignancy or radiotherapy, pregnancy or lactation, or insufficient bone height are unlikely to benefit or be eligible.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults who need a single molar replaced in a healed site with limited bucco‑lingual bone width will receive either a narrow‑diameter TiZr implant (≤3.5 mm) or a standard‑diameter implant to support a single crown. The study will track implant survival, peri‑implant tissue health, and prosthetic complications over follow‑up visits. Investigators will also record prosthetic parameters such as emergence angle and platform width and quantify occlusal/bite forces to explore their relationship with outcomes. The aim is to determine whether narrow TiZr implants can provide comparable clinical and technical performance in high‑load posterior sites without the need for bone augmentation.

Why it matters

Potential benefit: If successful, this approach could let some patients get a single molar replaced with a less invasive narrow TiZr implant and avoid bone grafting while maintaining good implant longevity.

How similar studies have gone: Previous clinical reports have shown favorable survival for narrow TiZr implants in various indications, but evidence is limited and inconsistent specifically for exclusive use under single crowns in high‑load molar sites.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aged ≥ 18 years.
* Require replacement of single missing molar tooth with dental implant in fully healed sites.
* Controlled oral hygiene (full-mouth plaque and bleeding scores ≤ 25% at baseline).
* Intact adjacent teeth and opposing dentition.
* Fully healed sites (≥ 6 months) with limited bone availability in the horizontal bucco-lingual dimension (residual bone width of ≤ 6 mm) and minimal height of 8 mm.
* Good compliance and commitment to attend follow-up review appointments.
* Willing to provide informed consent.

Exclusion Criteria:

* Localized/generalized periodontitis.
* Any medical condition that may contraindicate implant treatment (Bornstein et al., 2009).
* Bone metabolic disease and/or taking medications that affect bone metabolism.
* Long term use of non-steroidal anti-inflammatory medications.
* History of malignancy, radiotherapy or chemotherapy.
* Pregnant or lactating women.
* Smokers.
* Severe bruxism or parafunctional habits.
* Large occlusal discrepancies.

Where it's running

  • Mbru
    Dubai, United Arab Emirates
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.