GNRI and ASA Status to Predict Lung Complications After Major Abdominal Surgery in Older Adults
Official title: Contribution of the Geriatric Nutritional Risk Index in Addition to the American Society of Anesthesiologists Physical Status Classification for Predicting Postoperative Pulmonary Complications After Elective Major Abdominal Surgery in Geriatric Patients
Run by Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital · NCT07862777 · Data updated 2026-11-12
This study tests whether the GNRI, added to ASA status, helps predict postoperative lung problems in people 65 and older after elective major abdominal surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 65 Years and up |
| Sex | All |
| Enrollment | 170 (estimated) |
| Sponsor | Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Academic / other |
| Locations | 1 site (Yenimahalle, Ankara) |
| Status | Recruiting |
| Started | October 2, 2026 |
| Main results expected | July 1, 2027 |
| Study ends | August 1, 2027 |
| Registry record updated | October 7, 2026 |
| Trial ID | NCT07862777 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Candidates are adults 65 years or older scheduled for elective major abdominal surgery under general anesthesia (e.g., colorectal, gastrectomy, pancreatic, or major hepatobiliary procedures) who have ASA-PS I–IV and provide informed consent.
✕Probably not a fit
Patients with normal nutritional status or those not at risk for PPC may not see a direct benefit from GNRI-based risk stratification.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study looks at how preoperative nutrition, measured by GNRI, relates to the risk of postoperative pulmonary complications (PPC) after elective major abdominal surgery in older adults. It aims to see if GNRI provides additional predictive value beyond the ASA physical status classification. Researchers will analyze preoperative albumin and weight data to calculate GNRI and correlate it with PPC incidence. The study will help identify high-risk patients who might benefit from targeted preoperative optimization. No interventional treatment is described in the protocol.
Why it matters
Potential benefit: If GNRI improves risk prediction, clinicians could better identify high-risk patients and tailor perioperative care to reduce PPC.
How similar studies have gone: Prior research suggests nutritional status can influence PPC risk, supporting the potential usefulness of GNRI in risk prediction; however, this approach remains observational and not yet proven.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 65 years or older. * Scheduled for elective major abdominal surgery under general anesthesia, including colorectal surgery, gastrectomy, pancreatic surgery, or major hepatobiliary resection. * American Society of Anesthesiologists Physical Status (ASA-PS) class I, II, III, or IV. * Informed consent provided by the participant or their legal representative. Exclusion Criteria: * Emergency surgery. * Minor or superficial procedures that do not require major intra-abdominal surgery, such as diagnostic laparoscopy, simple laparoscopic cholecystectomy, or simple hernia repair. * Active pneumonia or acute respiratory failure before surgery. * Missing preoperative serum albumin, body weight, or height measurements. * Does not provide informed consent or withdraws from the study.
Where it's running
-
Dr. Abdurrahman Yurtaslan Ankara Oncology Hospital
Yenimahalle, Ankara, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: arif timuroglu — Dr. Abdurrahman yurtaslan Ankara Oncology Hospital
- Study coordinator: arif timuroglu, MD
- Email: ariftimuroglu@yahoo.com
- Phone: 05072601980
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.