Clinical trial Recruiting at 3 sites Observational Ages 18 and up

Genetic and molecular analysis of brain lesions

Official title: Genetic and Molecular Characterization of Nervous System Lesions

Run by Assistance Publique - Hôpitaux de Paris · NCT06314607 · Data updated 2026-11-12

This study is trying to better understand brain tumors and lesions by looking at their genetics and biology in patients who have had surgery, to help improve diagnosis and find new treatments.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment10000 (estimated)
SponsorAssistance Publique - Hôpitaux de Paris
Academic / other
Drugs / interventionschemotherapy
Locations3 sites (Paris and 2 other locations)
StatusRecruiting
StartedMarch 26, 2024
Main results expectedMarch 2034
Study endsMarch 2034
Registry record updatedSeptember 4, 2024
Trial IDNCT06314607 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients aged 18 and older who have been operated on for a brain lesion or are being followed up for such conditions.

Probably not a fit

Patients with brain lesions who are not undergoing surgical intervention or follow-up may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on the genetic and molecular characterization of brain tumors and lesions to improve diagnostic and prognostic classifications. It aims to refine the understanding of the biological mechanisms involved in these conditions and develop new targeted treatment strategies. The study involves the collection of biological samples from patients who have undergone surgery for brain lesions, including tumors and non-tumoral lesions. By utilizing advanced genomic techniques, the research seeks to enhance the classification of these pathologies and identify potential theranostic targets.

Why it matters

Potential benefit: If successful, this study could lead to more accurate diagnoses and personalized treatment options for patients with brain tumors and lesions.

How similar studies have gone: Other studies have shown success in utilizing genetic and molecular characterization for brain tumors, indicating a promising approach in this field.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Any patient operated on for a brain lesion (e.g. tumors: glioma, LCPSNC, meningioma, or rare tumor) and/or followed up for one of these pathologies.
* Age ≥ 18 years
* Consent or non-opposition of the patient or his/her legal representative (guardian) to participate in the study.

Exclusion Criteria: NA

Where it's running

  • Service de Neurochirurgie - Hôpital de la Pitié Salpêtrière
    Paris, France
    Recruiting
  • Service de Neurologie 2 -Hôpital de la Pitié Salpêtrière
    Paris, France
    Recruiting
  • Service de Radiothérapie - Hôpital de la Pittié Salpêtrière
    Paris, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.